Int Neurourol J.  2016 Sep;20(3):224-231. 10.5213/inj.1630490.245.

Stress Urinary Incontinence in Women With Multiple Sclerosis

• Massot C
• Khenioui H
• Agnani O
• Guyot MA
• Hautecoeur P
• Donze C

• KMID: 2365716
• DOI: http://doi.org/10.5213/inj.1630490.245

Abstract

PURPOSE
To report the prevalence and risk factors of stress urinary incontinence (SUI) and the prevalence of intrinsic sphincter deficiency in women with multiple sclerosis (MS).
METHODS
We conducted a retrospective study. Female patients with MS, followed for lower urinary tract symptoms (LUTS) during a 15-year period were included. Demographic data, MS history, expanded disability status scale (EDSS) score at the urodynamic visit, obstetrical past, birth weight, LUTS, and urodynamic findings were collected. SUI was defined as incontinence during cough, or any effort. A maximum urethral closure pressure less than 30 cm H2O defined intrinsic sphincter deficiency.
RESULTS
We included 363 women with a mean age of 46.7±10.8 years and a mean disease duration of 12.9±8.7 years. The incidence of relapsing remitting MS, a secondary progressive form, and a primary progressive form was 60.6%, 32.8%, and 6.6%, respectively. The prevalence of SUI was 31.4%. The prevalence of intrinsic sphincter deficiency was 1.4% and 0.8% of these patients had a SUI (P=0.300). In a multivariate analysis, women with a SUI had significantly higher birth weight (P=0.030), a pelvic organ prolapse (P=0.021), urgent urinary incontinence (P=0.006), a lower EDSS score (P=0.019), and a weaker containing effort (P<0.001).
CONCLUSIONS
The prevalence of SUI in women with MS was 31.4%. This symptom could affect the quality of life of women with MS.

Keyword

Urinary Incontinence, Stress; Multiple Sclerosis; Lower Urinary Tract Symptoms

MeSH Terms

Birth Weight
Cough
Female
Humans
Incidence
Lower Urinary Tract Symptoms
Multiple Sclerosis*
Multivariate Analysis
Pelvic Organ Prolapse
Prevalence
Quality of Life
Retrospective Studies
Risk Factors
Urinary Incontinence*
Urinary Incontinence, Stress
Urodynamics