J Cardiovasc Ultrasound.  2016 Dec;24(4):274-275. 10.4250/jcu.2016.24.4.274.

The Incremental Effect of Obesity on Myocardial Fibrosis In Patients with Aortic Stenosis

• Yoon SJ

• KMID: 2364643
• DOI: http://doi.org/10.4250/jcu.2016.24.4.274

Abstract

No abstract available.

MeSH Terms

Aortic Valve Stenosis*
Fibrosis*
Humans
Obesity*

Reference

1. López B, Querejeta R, Varo N, González A, Larman M, Martínez Ubago JL, Díez J. Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients. Circulation. 2001; 104:286–291.

2. Liu YW, Lee WH, Lin CC, Huang YY, Lee WT, Lee CH, Tsai LM, Chen JH, Tsai WC. Left ventricular diastolic wall strain and myocardial fibrosis in treated hypertension. Int J Cardiol. 2014; 172:e304–e306.

3. Dusenbery SM, Lunze FI, Jerosch-Herold M, Geva T, Newburger JW, Colan SD, Powell AJ. Left ventricular strain and myocardial fibrosis in congenital aortic stenosis. Am J Cardiol. 2015; 116:1257–1262.

4. Saito M, Okayama H, Yoshii T, Higashi H, Morioka H, Hiasa G, Sumimoto T, Inaba S, Nishimura K, Inoue K, Ogimoto A, Shigematsu Y, Hamada M, Higaki J. Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2012; 13:617–623.

5. Lai YH, Lo CI, Wu YJ, Hung CL, Yeh HI. Cardiac remodeling, adaptations and associated myocardial mechanics in hypertensive heart diseases. Acta Cardiol Sin. 2013; 29:64–70.

6. Kass DA. Ventricular arterial stiffening: integrating the pathophysiology. Hypertension. 2005; 46:185–193.

7. Muiesan ML, Salvetti M, Monteduro C, Bonzi B, Paini A, Viola S, Poisa P, Rizzoni D, Castellano M, Agabiti-Rosei E. Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients. Hypertension. 2004; 43:731–738.

8. Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996; 275:1557–1562.

9. Kehat I, Molkentin JD. Molecular pathways underlying cardiac remodeling during pathophysiological stimulation. Circulation. 2010; 122:2727–2735.

10. Hamdani N, Bishu KG, von Frieling-Salewsky M, Redfield MM, Linke WA. Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction. Cardiovasc Res. 2013; 97:464–471.

11. Mayet J, Hughes A. Cardiac and vascular pathophysiology in hypertension. Heart. 2003; 89:1104–1109.

12. Barasch E, Reichek N. Left ventricular hypertrophy in asymptomatic nonsevere aortic stenosis: should we worry? Circ Cardiovasc Imaging. 2015; 8:e004104.

13. Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR. Left ventricular hypertrophy with strain and aortic stenosis. Circulation. 2014; 130:1607–1616.

14. de Simone G, Pasanisi F, Contaldo F. Link of nonhemodynamic factors to hemodynamic determinants of left ventricular hypertrophy. Hypertension. 2001; 38:13–18.

15. Alpert MA. Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome. Am J Med Sci. 2001; 321:225–236.

16. Iacobellis G. Local and systemic effects of the multifaceted epicardial adipose tissue depot. Nat Rev Endocrinol. 2015; 11:363–371.

17. Pandit SV, Anumonwo J, Jalife J. Atrial fibrillation susceptibility in obesity: an excess adiposity and fibrosis complicity? Circ Res. 2016; 118:1468–1471.

18. Ávila-Vanzzini N, Fritche-Salazar JF, Vázquez-Castro NM, Rivera-Lara P, Pérez-Méndez O, Martínez-Herrera H, Gómez-Sánchez M, Aranda-Frausto A, Herrera-Bello H, Luna-Luna M, Arias Godínez JA. Echocardiographic and histologic correlation in patients with severe aortic stenosis: influence of overweight and obesity. J Cardiovasc Ultrasound. 2016; 24:303–311.

19. Tee MW, Won S, Raman FS, Yi C, Vigneault DM, Davies-Venn C, Liu S, Lardo AC, Lima JA, Noble JA, Emter CA, Bluemke DA. Regional strain analysis with multidetector CT in a swine cardiomyopathy model: relationship to cardiac MR tagging and myocardial fibrosis. Radiology. 2015; 277:88–94.

20. Kang SJ, Lim HS, Choi BJ, Choi SY, Hwang GS, Yoon MH, Tahk SJ, Shin JH. Longitudinal strain and torsion assessed by two-dimensional speckle tracking correlate with the serum level of tissue inhibitor of matrix metalloproteinase-1, a marker of myocardial fibrosis, in patients with hypertension. J Am Soc Echocardiogr. 2008; 21:907–911.