J Korean Med Assoc.  2016 Dec;59(12):912-915. 10.5124/jkma.2016.59.12.912.

Recent outbreaks of hepatitis C virus infection in Korea and strategy for prevention

• Kim IH

• KMID: 2364053
• DOI: http://doi.org/10.5124/jkma.2016.59.12.912

Abstract

Hepatitis C virus (HCV) is one of the major causes of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. In South Korea, the prevalence of HCV infection in adults is 0.78%. Recent outbreaks of HCV infection in Korea were associated with unsafe injection practices such as syringe reuse, contaminated multi-dose vials, and unsanitary medical procedures. The findings emphasize the role of unsafe injection practices in the community outbreak of hepatitis C, as well as the need to establish a routine surveillance system and increase awareness among health care workers regarding safe injection practices. In response to the HCV outbreaks, the Korean government and Korean Medical Association announced a strategy for prevention and control of HCV infection. It should encompass health care institutions as well as non-medical facilities providing invasive procedures carrying the risk of HCV transmission. Furthermore, the government needs to consider including an anti-HCV test in national health screening and broaden financial support for expensive novel oral anti-HCV drugs for early detection and eradication of HCV infection.

Keyword

Hepacivirus; Outbreak; Prevention & control

MeSH Terms

Adult
Carcinoma, Hepatocellular
Delivery of Health Care
Disease Outbreaks*
Financial Support
Hepacivirus*
Hepatitis C*
Hepatitis*
Hepatitis, Chronic
Humans
Korea*
Liver Cirrhosis
Mass Screening
Prevalence
Syringes

Reference

1. Jung YK. Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver: what has been changed? Treatment of chronic hepatitis C genotype 2 and 3. Korean J Gastroenterol. 2016; 67:132–136.

2. Lee SS, Byoun YS, Jeong SH, Kim YM, Gil H, Min BY, Seong MH, Jang ES, Kim JW. Type and cause of liver disease in Korea: single-center experience, 2005-2010. Clin Mol Hepatol. 2012; 18:309–315.

3. Kim DY, Kim IH, Jeong SH, Cho YK, Lee JH, Jin YJ, Lee D, Suh DJ, Han KH, Park NH, Kang HY, Jung YK, Kim YS, Kim KA, Lee YJ, Lee BS, Yim HJ, Lee HJ, Baik SK, Tak WY, Lee SJ, Chung WJ, Choi SK, Cho EY, Heo J, Kim DJ, Song BC, Kim MW, Lee J, Chae HB, Choi DH, Choi HY, Ki M. A nationwide seroepidemiology of hepatitis C virus infection in South Korea. Liver Int. 2013; 33:586–594.

4. Kim KA, Jeong SH, Jang ES, Kim YS, Lee YJ, Jung EU, Kim IH, Cho SB, Kee MK, Kang C. Geographic differences in the epidemiological features of HCV infection in Korea. Clin Mol Hepatol. 2014; 20:361–367.

5. Seong MH, Kil H, Kim YS, Bae SH, Lee YJ, Lee HC, Kang BH, Jeong SH. Clinical and epidemiological features of hepatitis C virus infection in South Korea: a prospective, multicenter cohort study. J Med Virol. 2013; 85:1724–1733.

6. Kermode M. Unsafe injections in low-income country health settings: need for injection safety promotion to prevent the spread of blood-borne viruses. Health Promot Int. 2004; 19:95–103.

7. Min JA, Yoon Y, Lee HJ, Choi J, Kwon M, Kim K, Lee CU, Kim DJ, Yun H. Prevalence and associated clinical characteristics of hepatitis B, C, and HIV infections among injecting drug users in Korea. J Med Virol. 2013; 85:575–582.