J Korean Burn Soc.  2016 Dec;19(2):57-61. 10.0000/jkbs.2016.19.2.57.

Serum Prealbumin Affected More by Serum CRP Than by Residual Burned Surface Area

• Yoo KT
• Woo GW
• Jang TY
• Song JS

• KMID: 2361627
• DOI: http://doi.org/10.0000/jkbs.2016.19.2.57

Abstract

PURPOSE
Prealbumin is known as a biochemical marker for assessing nutritional status, and it is influenced by a systemic inflammatory condition. This study aims to find any correlation between patients' low serum prealbumin in electrical burn and unhealed burn surface area and insufficient nutritional support.
METHODS
Data were collected by a review of the medical charts of patients admitted to Hanil General Hospital for electrical burn. Laboratory results such as prealbumin, albumin, total lymphocyte count (TLC), and C-reactive protein (CRP) were collected and tested every week. Residual burn surface area (residual BSA) during a specific period was calculated from the surgery record. Statistical analysis was conducted using Pearson's correlation and multiple regression analysis.
RESULTS
A total of 30 subjects were selected, all male. Average total burn surface area was 20.9±14.9%, and patients were operated on about three times after admission. There was statistical significance among all variables in Pearson's correlation test, but in multiple regression analysis, albumin and CRP were significant compared with prealbumin.
CONCLUSION
The results could indicate that burn causes a systemic inflammatory reaction, which could affect the serum prealbumin level. Further study concerning the biological plausibility of each variable is needed.

Keyword

Electric burns; Prealbumin; Transthyretin; Nutrition

MeSH Terms

Biomarkers
Burns*
Burns, Electric
C-Reactive Protein
Hospitals, General
Humans
Lymphocyte Count
Male
Nutritional Status
Nutritional Support
Prealbumin*
Biomarkers
C-Reactive Protein
Prealbumin