Ann Dermatol.  1995 Jul;7(3):231-235. 10.5021/ad.1995.7.3.231.

New Combination Therapy for Vitiligo: An Effective and Short Term Regimen

• Kim HY
• Park SL

• KMID: 2361376
• DOI: http://doi.org/10.5021/ad.1995.7.3.231

Abstract

BACKGROUND
The main therapeutic method currently used for the treatment of vitiligo vulgaris is either photochemotherapy or corticosteroids. But both of the procedures however require lengthy treatment to obtain a satisfactory result.
OBJECTIVE
To determine the increased efficacy of the combination therapy of photochemotherapy with corticosteroid and chlorpromazine compared with the usual monotherapy.
METHODS
The combination therapy was done in 29 cases and the results were compared with the results of either monotherapy appearing in the literatures.
RESULTS
f the 29 patients, 14(48.3%) patients achieved 100% repigmentation, 7(24.1%) patients 75~50%, 5(17.2%) patients 25~50%, and 3(10.4%) patients less than 25%. For the cured patients, 190.3 days and 32.7 times of photochemotherapy were used.
CONCLUSION
The combination therapy is more effective, and the duration of treatment can be greatly reduced compared with either monotherapy.

Keyword

Combination therapy; Vitiligo

MeSH Terms

Adrenal Cortex Hormones
Chlorpromazine
Humans
Methods
Photochemotherapy
Vitiligo*
Adrenal Cortex Hormones
Chlorpromazine