J Korean Med Sci.  2016 Feb;31(2):178-182. 10.3346/jkms.2016.31.2.178.

Patients Presenting with Advanced Human Immunodeficiency Virus Disease: Epidemiological Features by Age Group

• Kang CR
• Bang JH
• Cho SI
• Kim KN
• Lee HJ
• Ryu BY
• Cho SK
• Lee YH
• Oh MD
• Lee JK

• KMID: 2360039
• DOI: http://doi.org/10.3346/jkms.2016.31.2.178

Abstract

We explored factors influencing presentation with advanced human immunodeficiency virus (HIV) disease by age group. Data were derived from a city-wide cross-sectional survey of 759 HIV-infected adults living in Seoul, Korea. The significance of each observed factor was assessed via multivariate logistic regression. Of subjects aged 20-34 years, lower educational level had a positive influence on presentation with advanced HIV disease (adjusted odds ratio [aOR], 2.43; 95% confidence interval [CI], 1.36-4.34); those recently diagnosed with HIV were more likely to be presented with advanced HIV disease (aOR, 3.17; 95% CI, 0.99-10.2). Of the subjects aged 35-49 years, those w ith advanced HIV disease were more likely to have been diagnosed during health check-ups (aOR, 2.91; 95% CI, 1.15-7.32) or via clinical manifestations (aOR, 3.61; 95% CI, 1.39-9.36). Of the subjects aged > or = 50 years, presentation with advanced HIV disease was significantly more common in older subjects (aOR per increment of 5 years, 2.06; 95% CI, 1.32-3.23) and less common among individuals diagnosed with HIV in 2000-2006 (aOR, 0.18; 95% CI, 0.04-0.83). In conclusion, a lower educational level in younger subjects and more advanced age in older subjects positively influence the presentation of advanced HIV disease.

Keyword

HIV; Acquired Immune Deficiency Syndrome; Late Presentation; Early Detection; Seoul Metropolitan City; Low Education; Old Age

MeSH Terms

Adult
Age Factors
CD4 Lymphocyte Count
Cross-Sectional Studies
Demography
Female
HIV Infections/*diagnosis/*epidemiology
Humans
Logistic Models
Male
Middle Aged
Odds Ratio
Republic of Korea/epidemiology
Young Adult

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