Ann Dermatol.
1999 Apr;11(2):94-97. 10.5021/ad.1999.11.2.94.
A Case of Trichoblastic Fibroma
- KMID: 2359740
- DOI: http://doi.org/10.5021/ad.1999.11.2.94
Abstract
- Trichoblastic fibroma is a rare, benign trichogenic tumor that has both an epithelial and mesenchymal component. This tumor may be confused clinically and/or histologically with basal cell carcinoma and other tumors with hair follicle differentiation. We describe here a patient with trichoblastic fibroma on the nose. For further characterization of the tumor, we studied the bcl-2 expression in this case and compared it with those of trichoepitheliomas and basal cell carcinomas. The bcl-2 expression in this case and trichoepitheliomas were positive at the periphery of the tumor nest only, whereas those of basal cell carcinomas were positive diffusely throughout the tumor nest.
