J Korean Neurol Assoc.
2016 Nov;34(5):375-379. 10.17340/jkna.2016.4.17.
Corticobasal Syndrome Initially Presenting with Apraxia of Speech
- Affiliations
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- 1Department of Neurology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. wieber04@snu.ac.kr
- 2Department of Neurology, Seoul National University Hospital, Seoul, Korea.
- 3Department of Neurology, Gyeonggi Provincial Medical Center Ansung Hospital, Anseong, Korea.
- 4Department of Nuclear Medicine, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.
- KMID: 2359454
- DOI: http://doi.org/10.17340/jkna.2016.4.17
Abstract
- Apraxia of speech is a disorder of speech programming and planning. We report a 64-year-old woman presenting with progressive apraxia of speech that evolved into right-side-dominant akinesia-rigidity syndrome over a 7-year period. Her motor symptoms were highly consistent with corticobasal syndrome, and neuroimaging revealed atrophy and hypometabolism in the left premotor and supplementary motor areas, which are relevant to apraxia of speech. This case illustrates that apraxia of speech may be an initial manifestation of corticobasal syndrome.
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