Korean J Anesthesiol.  1979 Dec;12(4):456-459.

Effect of Mixed Intravenous Administration of Succinylcholine and Pancuronium on the Intraocular Pressure ( IOP )

• Im WM
• Lee CB

Abstract

Succinylcholine has been reported to cause elevation of intraocular pressure(IOP.) IOP measurements, following single and mixed intravenous administration of succinylcholine and pancuronium, given immediately after thiopental, were made in 40 surgical patients, to assess the effect of pacuronium on the succinylcholine induced increase in IOP. The major findings of this study were as follows; 1) Tbiopental showed significant lowering effect on IOP. 2) A single intravenous injection of succinylcholine(1mg/kg) caused a slight rise of lOP. 3) A single intravenous injection of pancuronium(4mg) caused a slight decrease of IOP. 4) A mixed intravenous injection of succinylcholine and pancuronium increased the IOP more significantly than succinylcholine alone, This also means that pancuronium do not inhibit succinylcholine induced increase In IOP. 5) Tracheal intubation caused a rise of IOP significantly.

MeSH Terms

Administration, Intravenous*
Humans
Injections, Intravenous
Intraocular Pressure*
Intubation
Pancuronium*
Succinylcholine*
Thiopental
Pancuronium
Succinylcholine
Thiopental