J Clin Neurol.  2016 Apr;12(2):248-250. 10.3988/jcn.2016.12.2.248.

A Novel Case of Solitary Cerebral Toxoplasmosis Mimicking Glioblastoma as the First Presentation of HIV

• León Ruiz M

• KMID: 2354151
• DOI: http://doi.org/10.3988/jcn.2016.12.2.248

Abstract

No abstract available.

MeSH Terms

Glioblastoma*
HIV*
Toxoplasmosis, Cerebral*

Figure

• 

  Fig. 1 A: Post-contrast axial cranial CT scan. It becomes apparent an extensive fronto-parietal hypodensity with mass effect, reaching contralateral hemisphere in a "butterfly-like" mode, and producing midline displacement. B: Gadolinium-enhanced axial T1-weighted brain MRI. MRI results confirmed CT scan findings, defining lesion as a large intra-axial ring-enhancing mass and extensive surrounding edema, giving rise to subfalcine herniation. C: Cerebral biopsy. In optical microscope, free tachyzoites (blue arrows) and pseudocyst bradyzoites (green arrows) around necrotic lesions be observe (hematoxylin and eosin stain, ×100). D: Zoite formations tested positive (dark brown stain) for anti-Toxoplasma antibody (×40). E: Brain tissue sample. Anti-HIV p24 antibody immunohistochemical stain (×40) demonstrates the presence of HIV antigen (dark brown stain).

Reference

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