Blood Res.  2016 Sep;51(3):206-207. 10.5045/br.2016.51.3.206.

A case of histoplasmosis in a patient with MDS/MPN-U

Affiliations
  • 1Department of Hematology and Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. nkkalson@yahoo.co.in
  • 2Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

No abstract available.


MeSH Terms

Histoplasmosis*
Humans

Figure

  • Fig. 1 (A) Peripheral blood shows neutrophils with toxic granules and two intra-cytoplasmic yeast forms of Histoplasma capsulatum in the cell on the left (May-Grunwald Giemsa, ×1,000). Inset: The fungus was brightly positive for periodic acid–Schiff stain (hematoxylin counterstain, ×1,000). (B) Hemodilute bone marrow smears showed dysgranulopoiesis with 5% blasts (May-Grunwald Giemsa, ×1,000). Inset: Ring sideroblasts comprised 32% of all cells (Perls' Prussian Blue reaction with neutral red counterstain, ×1,000). (C) Bone marrow biopsy showed intracellular yeast forms (hematoxylin and eosin, ×400). Inset: These were positive for Grocott's silver methenamine stain (methyl green counterstain, ×1,000). (D) Lactophenol cotton blue wet-mount preparation of the isolated mold shows thick-walled and tuberculate macroconidia, with a close-up in the inset (lactophenol cotton blue stain, ×1,000).


Reference

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