Ewha Med J.  2003 Jun;26(2):193-196. 10.12771/emj.2003.26.2.193.

A Case of NSAIDs Induced Massive Small Bowel Bleeding in Behcet's Disease

• Kang IS
• Rye YJ
• Chang JE
• Jung SA
• Lee J
• Cho YJ
• Lee KE
• Lee J

• KMID: 2352873
• DOI: http://doi.org/10.12771/emj.2003.26.2.193

Abstract

Bechet's disease(BD) is a chronic inflammatoroy condition involving several organs including gastrointestinal tract. Gastrointestinal tracts involvement in BD has been identified throughout the entire alimentary tract and commonly accompanies ulcerative lesions in the small and large bowel. It is debatable whether BD could be included among seronegative spondyloarthropathy (SPA).SPA usually occurs without overt sign of intestinal inflammation, but significant number of patients have asymptomatic intestinal inflammation, usually affecting ileum. Since most patients with SPA including BD are treated with NSAIDS. However, NSAID may play a role in aggravation or provocation of intestinal inflammation. Special attention to asymptomatic intestinal inflammation is needed, especially when NSAIDs are used for management of arthritic symptom in SpA. We experienced a case of BD which was complicated by a massive small bowel bleeding precipitated by NSAID use.

Keyword

Behcet's disease; NSAIDs; Small bowel bleeding

MeSH Terms

Anti-Inflammatory Agents, Non-Steroidal*
Gastrointestinal Tract
Hemorrhage*
Humans
Ileum
Inflammation
Spondylarthropathies
Ulcer
Anti-Inflammatory Agents, Non-Steroidal