Nucl Med Mol Imaging.
2016 Sep;50(3):255-257. 10.1007/s13139-016-0427-8.
Cowden Syndrome Detected by FDG PET/CT in an Endometrial Cancer Patient
- Affiliations
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- 1Department of Nuclear Medicine, Eulji University Hospital, Daejeon, Republic of Korea.
- 2Department of Pathology, Eulji University Hospital, Daejeon, Republic of Korea.
- 3Department of Radiology, The Catholic University of Korea, Daejeon Saint Mary's Hospital, Daejeon, Republic of Korea. greempark@gmail.com
- KMID: 2351650
- DOI: http://doi.org/10.1007/s13139-016-0427-8
Abstract
- Cowden syndrome (CS) is a rare autosomal dominant disorder characterized by multiple hamartomas in various tissues and cancers (breast, thyroid, and endometrium). We report CS of the esophagus and gastrointestinal tract that was incidentally detected by positron emission tomography/computed tomography (PET/CT) at postoperative surveillance in an endometrial cancer patient. PET/CT showed mildly increased FDGuptake along the entire esophagus and stomach. Upper GI endoscopy and histologic examination revealed glycogenic acanthosis of the esophagus and several hundred gastric polyps. In our case, increased FDG uptake of the esophageal wall contributed to the diagnosis of CS.
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