J Pathol Transl Med.  2016 Jul;50(4):322-324. 10.4132/jptm.2015.11.24.

Primary Cutaneous Adenoid Cystic Carcinoma Arising in Umbilicus

• Lee SJ
• Yang WI
• Kim SK

• KMID: 2345559
• DOI: http://doi.org/10.4132/jptm.2015.11.24

Abstract

No abstract available.

MeSH Terms

Adenoids*
Carcinoma, Adenoid Cystic*
Umbilicus*

Figure

• 

  Fig. 1. Macroscopic findings of tumor arising in umbilicus. (A) An ill-defined bean-sized erythematous lesion on the umbilicus. (B) In sections of the specimen from the Mohs micrographic surgery, cut surfaces had an infiltrative firm mass.

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  Fig. 2. Microscopic findings of primary cutaneous adenoid cystic carcinoma. (A) Images of basaloid cells that have infiltrated the dermis and the subcutaneous layer, but not the epidermis. Note the tumor cells’ arrangement in nests and their cribriform pattern. (B) Images showing the cribriform and tubular growth patterns of the tumor, which also have a solid portion. (C) Perineural invasion by the tumor.

• 

  Fig. 3. Immunohistochemical staining results of primary cutaneous adenoid cystic carcinoma. Immunohistochemical staining images showing strong expression of epithelial membrane antigen (A) and KIT (B) in tumor cells.

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