Ann Dermatol.  2016 Aug;28(4):529-531. 10.5021/ad.2016.28.4.529.

A Rare Cutaneous Adverse Reaction after Intra-Articular Injection of Hyaluronic Acid

Affiliations
  • 1Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea. ahnsk@yonsei.ac.kr

Abstract

No abstract available.


MeSH Terms

Hyaluronic Acid*
Injections, Intra-Articular*
Hyaluronic Acid

Figure

  • Fig. 1 Diffuse edematous erythema, vesicles and bullae with localized erosion on the patient's left arm and trunk. Arrows present injection sites and courses; dotted arrows mean that injection site is on her scapula of the back area.

  • Fig. 2 Severe papillary dermal edema and superficial perivenular mixed inflammatory cell infiltrates with an increased number of eosinophils (H&E, ×100; inset, ×400).


Reference

1. Petrella RJ, Petrella M. A prospective, randomized, double-blind, placebo controlled study to evaluate the efficacy of intraarticular hyaluronic acid for osteoarthritis of the knee. J Rheumatol. 2006; 33:951–956.
2. Calvo M, Tornero P, De Barrio M, Mínquez G, Infante S, Herrero T, et al. Erytema multiform due to hyaluronic acid (go-on). J Investig Allergol Clin Immunol. 2007; 17:127–128.
3. Kim JH, Choi JS, Yun JH, Kang HK, Baek JO, Roh JY, et al. Foreign body reaction to injectable hyaluronic acid: late granuloma formation. Ann Dermatol. 2015; 27:224–225.
Article
4. Kunugiza Y, Tani M, Tomita T, Yoshikawa H. Staphylococcal scalded skin syndrome after intra-articular injection of hyaluronic acid. Mod Rheumatol. 2011; 21:316–319.
Article
5. Micheels P. Human anti-hyaluronic acid antibodies: is it possible? Dermatol Surg. 2001; 27:185–191.
Article
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