J Korean Neurol Assoc.  2013 Nov;31(4):254-257.

Anti-GM1 Antibody Associated Acute Motor Conduction Block Neuropathy Presenting With Reversible Conduction Failure

Affiliations
  • 1Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yepark407@gmail.com
  • 2Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
  • 3Department of Neurology, Dong-A University College of Medicine, Busan, Korea.

Abstract

A 57-year-old man developed motor weakness and paresthesia after acute enteritis. Nerve conduction study revealed decreased compound muscle action potentials in median nerves and conduction blocks in ulnar nerves. Serum IgG anti-GM1 antibody was positive. Conduction blocks rapidly disappeared through sequential studies, which are defined as reversible conduction failure (RCF). This study represents anti-GM1 antibody-associated acute motor conduction block neuropathy based on RCF. We underline that serial nerve conduction studies might be required for characterization of clinical and electrophysiological features.

Keyword

Reversible conduction failure; Acute motor conduction block neuropathy; Anti-GM1 antibody

MeSH Terms

Action Potentials
Enteritis
Humans
Immunoglobulin G
Median Nerve
Middle Aged
Muscles
Neural Conduction
Paresthesia
Ulnar Nerve
Immunoglobulin G
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