J Korean Neurol Assoc.  2007 Aug;25(3):416-418.

A Case of MELAS with Maternally Transmitted Type II Diabetes Mellitus and Deafness

Affiliations
  • 1Department of Neurology, Bundang Jesaeng General Hospital, Korea. yhj3140@daum.net
  • 2Department of Neurology, College of Medicine, Hanyang University, Korea.

Abstract

MELAS syndrome is typically a multisystemic disorder. We report one case of MELAS showing both maternally transmitted type II diabetes mellitus (DM) and deafness. A 41-year-old woman was admitted because of severe headache and vomiting. She developed type II DM at age 26 and was followed by bilateral sensorineural type hearing loss at age 37. Family history revealed that her mother and two sisters suffered from similar disorders. MELAS with A3243G point mutation was confirmed in the patient and her daughter.

Keyword

MELAS; Deafness; Diabetes

MeSH Terms

Adult
Deafness*
Diabetes Mellitus*
Female
Headache
Hearing Loss
Humans
MELAS Syndrome*
Mothers
Nuclear Family
Point Mutation
Siblings
Vomiting
Full Text Links
  • JKNA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr