J Korean Med Assoc.  2011 Oct;54(10):1028-1035.

Evidence-based National Cancer Screening program of Korea

• Lee WC

Abstract

Cancer is the leading cause of death in Korea. Therefore cancer control is one of the most important health issues. Cancer screening is the most promising strategy for controlling cancer. The National Cancer Screening Program started in 2002 in Korea. The goal of the program is to reduce the mortality or incidence rate of the cancer or both. To be effective, the evidence-based National Cancer Screening program should be implemented. For the evidence-based program, related indices were recommended for each step. When adopting a new cancer screening program, the predicted benefit and harm should be analysed, and when a decision is made to adopt the program, a pilot study for feasibility should be implemented. After implementing the community-based screening program, several types of the evaluation for the effectiveness of the program ought to be performed. The indices for each step were listed and discussed. And several conditions suggested for performing evidence-based national cancer screening program in Korea were discussed. Randomized clinical trials to compare the efficacy between the screening tools are recommended. And the study to evaluate the harm from the screening programs should be performed. To achieve the goal of the National Cancer Screening Program, evidence-based national cancer screening program should be performed.

Keyword

Evidence-based; National Cancer Screening Program; Mortality reduction; Harm

MeSH Terms

Cause of Death
Early Detection of Cancer
Incidence
Korea
Mass Screening

Reference

1. STATISTICS KOREA. Annual Report on the Causes of Death Statistics. 2011. Taejon: Statistical Office.

2. The Ministry of Health and Welfare. Cancer Control 2015 - 2nd period of 10 year plan for National Cancer Control. 2006. Seoul:

3. Mausner JS, Kramer S. Epidemiology: an introductory text. 1985. 2nd ed. Philadelphia: W. B. Saunders.

4. Wilson JMG, Jungner F. Principles and practice of screening for disease(Public Health Papers No. 34). 1968. Geneva: WHO.

5. The Ministry of Health and Welfare. Public Notification No. 2010-129 of the Ministry of Health and Welfare, Standard of National Cancer Screening Program. 2010.

6. Dowling EC, Klabunde C, Patnick J, Ballard-Barbash R. International Cancer Screening Network (ICSN). Breast and cervical cancer screening programme implementation in 16 countries. J Med Screen. 2010. 17:139–146.

7. Benson VS, Patnick J, Davies AK, Nadel MR, Smith RA, Atkin WS. International Colorectal Cancer Screening Network. Colorectal cancer screening: a comparison of 35 initiatives in 17 countries. Int J Cancer. 2008. 122:1357–1367.

8. Lee WC. Park JK, editor. Cancer Screening. Oncology. 2003. Seoul: Ilchogak;246–249.

9. Heresbach D, Manfredi S, D'halluin PN, Bretagne JF, Branger B. Review in depth and meta-analysis of controlled trials on colorectal cancer screening by faecal occult blood test. Eur J Gastroenterol Hepatol. 2006. 18:427–433.

10. The Ministry of Health and Welfare. Public Notification No. 2010-120 of the Ministry of Health and Welfare, Standard of National Health Screening Program. 2010.

11. Fletcher SW, Black W, Harris R, Rimer BK, Shapiro S. Report of the International Workshop on Screening for Breast Cancer. J Natl Cancer Inst. 1993. 85:1644–1656.

12. English colorectal cancer screening pilot information pack [Internet]. cited 2011 Sep 19. Sheffield: NHS Cancer Screening Programmes;Available from: http://www.cancerscreening.nhs.uk/bowel/information-pack/index.html.

13. Shapiro S, Venet W, Strax P, Venet L, Roeser R. Ten- to fourteen-year effect of screening on breast cancer mortality. J Natl Cancer Inst. 1982. 69:349–355.

14. Kerlikowske K, Grady D, Rubin SM, Sandrock C, Ernster VL. Efficacy of screening mammography. A meta-analysis. JAMA. 1995. 273:149–154.

15. Andriole GL, Crawford ED, Grubb RL 3rd, Buys SS, Chia D, Church TR, Fouad MN, Gelmann EP, Kvale PA, Reding DJ, Weissfeld JL, Yokochi LA, O'Brien B, Clapp JD, Rathmell JM, Riley TL, Hayes RB, Kramer BS, Izmirlian G, Miller AB, Pinsky PF, Prorok PC, Gohagan JK, Berg CD. PLCO Project Team. Mortality results from a randomized prostate-cancer screening trial. N Engl J Med. 2009. 360:1310–1319.

16. Schroder FH, Hugosson J, Roobol MJ, Tammela TL, Ciatto S, Nelen V, Kwiatkowski M, Lujan M, Lilja H, Zappa M, Denis LJ, Recker F, Berenguer A, Maattanen L, Bangma CH, Aus G, Villers A, Rebillard X, van der Kwast T, Blijenberg BG, Moss SM, de Koning HJ, Auvinen A. ERSPC Investigators. Screening and prostate-cancer mortality in a randomized European study. N Engl J Med. 2009. 360:1320–1328.

17. Black WC. Overdiagnosis: an underrecognized cause of confusion and harm in cancer screening. J Natl Cancer Inst. 2000. 92:1280–1282.

18. Annual report of cancer statistics in Korea in 2008. Gyeonggi. 2010. Ministry of Health & Welfare, Korea Central Cancer Registry, National Cancer Center.

19. Taplin SH, Mandelson MT. Principles of cancer screening for clinicians. Prim Care. 1992. 19:513–533.

20. Schroder FH, Albertsen P. Open to debate. The motion: there is evidence that prostate cancer screening does more good than harm. Eur Urol. 2006. 50:377–380.

21. U.S. Preventive Services Task Force. Guide to clinical preventive services: report of the U.S. Preventive Services Task Force. 2002. Alexandria: International Medical Publishing.

22. NHS. Evaluation of the prostate cancer screening programme against the NSC handbook criteria. 2011. London: UK National Screening Committee.

23. Lazcano-Ponce EC, Moss S, Alonso de Ruiz P, Salmeron Castro J, Hernandez Avila M. Cervical cancer screening in developing countries: why is it ineffective? The case of Mexico. Arch Med Res. 1999. 30:240–250.

24. Vainio H, Bianchini F. IARC Handbooks of Cancer Prevention: Breast Cancer Screening. 2002. vol 7. LYON: IARC Press.

25. Yoon SH, Yim HW, Lee WC. Bias in cancer screening evaluation. Korean J Epidemiol. 2008. 30:12–24.

26. Lee SY, Lee WC, Koo JW, et al. Comparison of Sensitivity and Specificity between endoscopy and UGIS for stomach cancer screening. Annual Meeting for Society of Korean Preventive Medicine. Oct 25, 2001; Sokcho.

27. Park EC. Cost and effectiveness of National Cancer Control Program of Korea. the 30th Forum for cancer control. May 9, 2011; Seoul. National Cancer Center, the Ministry of Health and Welfare.

28. Ministry of Health & Welfare. Act No.10333. whole Amended. Cancer Control Act. 2010. 05. 31.

29. Ministry of Health & Welfare. Act No.10333. Other Laws and Regulations Amended. Framework Act on Health Examination. 2010. 05. 31.