J Korean Med Assoc.  2010 Feb;53(2):164-168.

Cancer Pain Management-Nonopoid Analgesics

• Kim DH

Abstract

Cancer pain patients have various diagnosis, stage of disease, response to pain, and treatments and individualized treatment methods are thus needed. Use of Nonopioid analgesics is the first step treatment (according to WHO ladder) for mild to moderate pain, and may be useful for second or third step treatments when combined with weak or strong opioids to reduce side effects of opioids and to create synergy between the two drugs. Acetaminophen and nonsteroidal antiinflammatory drugs(NSAIDs) are also nonopioid analgesics. NSAIDs have a ceiling effect, along with antipyretic, analgesic and antiinflammatory effects, while not producing physical and psychological dependence. Adverse effects of NSAIDs include gastrointestinal hemorrhage, coagulopathy, and deterioration of renal function.

Keyword

Acetaminophen; Cancer pain; Nonopioid analgesics; Nonsteroidal antiinflammatory drugs (NSAIDs); Opioids

MeSH Terms

Acetaminophen
Analgesics
Analgesics, Non-Narcotic
Analgesics, Opioid
Anti-Inflammatory Agents, Non-Steroidal
Gastrointestinal Hemorrhage
Humans
Resin Cements
Acetaminophen
Analgesics
Analgesics, Non-Narcotic
Analgesics, Opioid
Anti-Inflammatory Agents, Non-Steroidal
Resin Cements

Reference

1. The korean pain society. Pain Medicine. 2007. 3rd ed. Seoul: Koonja Publishing;425–442.

2. Parris WCV, Eriator I. Smith HS, editor. Cancer pain management. Current theapy in pain. 2009. Philadelphia: Saunders Elsevier;97–106.

3. Kim MJ, Park JA, Shin SJ. Pain and pain management in hospitalized cancer patients. J Korean Acad Fundam Nurs. 2008. 15:161–170.

4. Heo DS. Pharmacologic management of cancer pain. J Korean Med Assoc. 2004. 47:268–276.

5. Baik SW, Byeun BM, Chae MG. The clinical evaluation in cancer pain management. Korean J Pain. 1998. 11:214–219.