J Korean Ophthalmol Soc.  2012 Oct;53(10):1472-1479.

The Changes in Central Macular Thickness after Cataract Surgery in Patients with Diabetic Retinopathy

• An TS
• Park IW
• Kwon SI

Abstract

PURPOSE
To evaluate the changes in central macular thickness (CMT) and incidence of macular edema (ME) after cataract surgery in diabetic patients compared with non-diabetic patients using optical coherence tomography (OCT).
METHODS
The records of 138 diabetic patients and 34 non-diabetic patients who underwent cataract surgery were retrospectively reviewed. The diabetic group was divided into 5 groups according to severity of diabetic retinopathy. The diabetic group was also divided into 2 groups depending on prior panretinal photocoagulation history. The changes in CMT were examined using OCT before cataract surgery and 1 week, 1-, 2- and 6-months after surgery in diabetic and non-diabetic patients.
RESULTS
The incidence of ME in the diabetic group and non-diabetic group was 19.6% and 2.9% respectively. The increased amount of CMT (DeltaCMT) was significantly greater in the diabetic group compared with the non-diabetic group during the observation period (p < 0.05). The DeltaCMT of eyes without a history of panretinal photocoagulation was statistically greater compared to the eyes with a history of panretinal photocoagulation at 1-, 2- and 6-months after cataract surgery (p = 0.005, 0.002, 0.008, respectively).
CONCLUSIONS
The DeltaCMT and incidence of ME were significantly greater in the diabetic group compared with the non-diabetic group. Additionally, the incidence of ME was significantly greater depending on severity of diabetic retinopathy in the diabetic group.

Keyword

Cataract surgery; Central macular thickness; Diabetic retinopathy; Macular edema; Panretinal photocoagulation

MeSH Terms

Cataract
Diabetic Retinopathy
Eye
Humans
Incidence
Light Coagulation
Macular Edema
Retrospective Studies
Tomography, Optical Coherence

Figure

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  Figure 1 The change in mean central macular thickness in diabetic patient group and non-diabetic patient group after cataract surgery. Paired t-test (p < 0.05). Wilcoxon signed rank test (p < 0.05). POD = postoperative day; NPDR = nonproliferative diabetic retinopathy; PDR = proliferative diabetic retinopathy; CMT = central macular thickness.

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  Figure 2 The change in postoperative mean central macular thickness compared to preoperative mean central macular thickness (Post Op. CMT / Pre Op. CMT) in diabetic patient group and non-diabetic patient group after cataract surgery. Student t-test (p < 0.05). Mann-Whitney U test (p < 0.05). POD = postoperative day; NPDR = nonproliferative diabetic retinopathy; CMT = central macular thickness.

• 

  Figure 3 The change in postoperative mean central macular thickness compared to preoperative mean central macular thickness (Post Op. CMT / Pre Op. CMT) in eyes with and without prior panretinal photocoagulation after cataract surgery. Student t-test (p < 0.05). Mann-Whitney U test (p < 0.05). POD = postoperative day; PRP = panretinal photocoagulation; CMT = central macular thickness.

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