J Korean Ophthalmol Soc.  2012 Feb;53(2):306-310.

Intraocular Pressure and Ocular Biometry Change of Healthy Eyes in Postural Variation

• Cho HJ
• Hwang YH
• Lee JH

Abstract

PURPOSE
To investigate intraocular pressure (IOP) and ocular biometry change according to the posture change in healthy eyes.
METHODS
Forty eight eyes of 48 healthy young subjects were enrolled. IOP, central anterior chamber depth (cACD), and axial length were measured after keeping each position for 10 minutes (upright, sitting, supine, and prone positions) by using the TonoPen(R) and A-scan ultrasonography.
RESULTS
Mean IOP was 19.68 +/- 2.15 mm Hg in prone position, 17.19 +/- 1.33 mm Hg in supine position, 16.49 +/- 1.76 mm Hg in sitting position, and 15.33 +/- 1.34 mm Hg in upright position. Difference among the positions was statistically significant (p < 0.01). Mean cACD was 3.68 +/- 0.35 mm in upright position, 3.63 +/- 0.32 mm in supine position, 3.59 +/- 0.34 mm in sitting position, and 3.47 +/- 0.30 mm in prone position. Difference among the positions was statistically significant (p < 0.01) except for the difference between supine and sitting position. Linear regression analysis revealed that cACD was significantly associated with IOP in prone position (R2 = 0.139, p < 0.01).
CONCLUSIONS
There was a significant change in IOP and cACD according to the posture change. cACD was significantly associated with IOP only in prone position.

Keyword

Anterior chamber depth; Body posture; Intraocular pressure; Prone position

MeSH Terms

Anterior Chamber
Biometry
Eye
Intraocular Pressure
Linear Models
Posture
Prone Position
Supine Position

Figure

• 

  Figure 1 Measurement of the intraocular pressure and central anterior chamber depth in prone position.

Reference

1. Allingham RR, Shields MB, Freedman S, et al. Shields' Textbook of Glaucoma. 2005. Philadelphia: Lippincott Williams & Wilkins;1–2.

2. Van Buskirk EM, Cioffi GA. Glaucomatous optic neuropathy. Am J Ophthalmol. 1992. 113:447–452.

3. Wüthrich UW. Postural change and intraocular pressure in glaucomatous eyes. Br J Ophthalmol. 1976. 60:111–114.

4. Leonard TJ, Kerr Muir MG, Kirkby GR, Hitchings RA. Ocular hypertension and posture. Br J Ophthalmol. 1983. 67:362–366.

5. Tsukahara S, Sasaki T. Postural change of IOP in normal persons and in patients with primary wide open-angle glaucoma and low-tension glaucoma. Br J Ophthalmol. 1984. 68:389–392.

6. Stambough JL, Dolan D, Werner R, Godfrey E. Ophthalmologic complications associated with prone positioning in spine surgery. J Am Acad Orthop Surg. 2007. 15:156–165.

7. Singer MS, Salim S. Bilateral acute angle-closure glaucoma as a complication of facedown spine surgery. Spine J. 2010. 10:e7–e9.

8. Harris LS, Galin MA. Prone provocative testing for narrow angle glaucoma. Arch Ophthalmol. 1972. 87:493–496.

9. Neumann E, Hyams SW. Gonioscopy and anterior chamber depth in the prone-position provocative test for angle-closure glaucoma. Ophthalmologica. 1973. 167:9–14.

10. Hyams SW, Friedman Z, Neumann E. Elevated intraocular pressure in the prone position. A new provocative test for angle-closure glaucoma. Am J Ophthalmol. 1968. 66:661–672.

11. Vaz F, Gupta AK. The influence of posture on intraocular pressure. Indian J Ophthalmol. 1981. 29:1–3.

12. Lam AK, Douthwaite WA. Does the change of anterior chamber depth or/and episcleral venous pressure cause intraocular pressure change in postural variation? Optom Vis Sci. 1997. 74:664–667.

13. Sano R, Kurokawa T, Kurimoto Y, et al. Comparison between the anterior chamber configuration in the supine position and that in the prone position in patients with narrow angle. Nihon Ganka Gakkai Zasshi. 2001. 105:388–393.

14. Lanzl IM, Merté RL, Graham AD. Does head positioning influence anterior chamber depth in pseudoexfoliation syndrome? J Glaucoma. 2000. 9:214–218.

15. Ermis SS. Effects of postural variation on anterior chamber depth in pseudoexfoliative eyes with normal intraocular pressure. Curr Eye Res. 2010. 35:888–891.

16. Lim LS, Saw SM, Jeganathan VS, et al. Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye study. Invest Ophthalmol Vis Sci. 2010. 51:103–109.