J Korean Ophthalmol Soc.  2012 Feb;53(2):291-296.

Comparison of 180degrees and 360degrees Selective Laser Trabeculoplasty

• Jang YS
• Kim JM
• Lim TH
• Kim HK
• Sohn YH

Abstract

PURPOSE
To compare the effect and safety of two regimens of Selective Laser Trabeculoplasty (SLT), SLT on 180degrees of trabecular meshwork and SLT with 100 laser spots on 360degrees of trabecular meshwork in patients with primary open-angle glaucoma and ocular hypertension.
METHODS
In a retrospective clinical study, the authors compared the pressure-lowering effects of SLT in two groups of patients; group 1 (83 patients) received SLT on 180degrees, group 2 (30 patients) on 360degrees of trabecular meshwork. The clinical outcome indicators included intraocular pressure (IOP) at one day, one week, one month, two months, three months and six months after SLT, and the anterior chamber reaction at post-laser one day.
RESULTS
There was no statistically significant difference in the IOP reduction between these two regimens after six months. The anterior chamber reactions in the two groups were significantly different (group 1; 0.61 +/- 0.64, group 2; 1.25 +/- 0.83, p = 0.001). The success rate of group 2 (43.3%) was not different from that of group 1 (31.3%; p = 0.23).
CONCLUSIONS
SLT on 180degrees of trabecular meshwork had a similar effect compared to that of SLT on 360degrees of trabecular meshwork in terms of IOP reduction. The authors of the present study suggest that 180degrees SLT is the safest procedure with regard to success rate and complications.

Keyword

Glaucoma; Ocular hypertension; Primary open-angle glaucoma; Selective laser trabeculoplasty

MeSH Terms

Anterior Chamber
Glaucoma
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Ocular Hypertension
Retrospective Studies
Shiga Toxin 1
Trabecular Meshwork
Trabeculectomy
Shiga Toxin 1

Figure

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  Figure 1 Meal IOP changes during follow-up period.

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  Figure 2 Mean IOP reduction percentage during follow-up period.

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  Figure 3 Kaplan-Meier survival curve using definition (failure defined as a need for additional SLT or glaucoma surgery): There were no significant statistical differences between the two groups during the follow-up period. Cumulative survival rate during each period: 1 month -180° 90.4%, 360° 83.3%; 2 months -180° 73.5%, 360° 76.7%; 3 months -180° 66.3%, 360° 73.3%; 6 months -180° 31.3%, 360° 43.3%, p = 0.25 (Log rank [Mantel-Cox] test).

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