J Korean Ophthalmol Soc.  2007 Nov;48(11):1473-1478.

Corneal Endothelial Cell Change with Different Phacoemulsification Time in Diabetic Patients

• Kim CJ
• Choi SK

Abstract

PURPOSE: To investigate the difference in corneal endothelial cell loss between diabetic and non-diabetic patients who were divided by the degree of phacoemulsification time after phacoemulsification with intraocular lens implantation.
METHODS
Forty eyes of 30 patients with diabetes and 47 eyes of 36 patients without diabetes were divided by phacoemulsification time into 3 groups: less than 40 seconds, from 40 to 80 seconds and over 80 seconds. The corneal endothelial cell density was compared before and 1, 4 and 16 weeks after phacoemulsification by one-way ANOVA. Bivariate correlation analysis was used to identify the correlation between phacoemulsification time and the endothelial density before and 1, 4 and 16 weeks after phcoemulsification.
RESULTS
The endothelial cell densities in diabetic and non-diabetic patients with different phacoemulsification time were not significantly different when compared before and 1, 4 and 16 weeks after phacoemulsification (P>0.05). Phacoemulsificaiton time and endothelial cell loss at 1, 4 and 16 weeks also showed no significant correlation.
CONCLUSIONS
Diabetes and differences in phacoemulsification time had no significant influence on corneal endothelial cell loss. This result suggests uncomplicated phacoemulsificaion is a safe method for cataract extraction in patients with or without diabetes.

Keyword

Cataract; Cornea; Diabetes; Endothelium; Phacoemulsification

MeSH Terms

Cataract
Cataract Extraction
Cornea
Corneal Endothelial Cell Loss
Endothelial Cells*
Endothelium
Humans
Lens Implantation, Intraocular
Phacoemulsification*

Figure

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  Figure 1. This shows the corneal endothelial cell density between pre and postoperative periods in diabetics and non-diabetics (cells/mm2). The cell densities were not statistically significantly different before and 1, 4, and 16 weeks after cataract surgery both in diabetics and in non-diabetics (P>0.05).

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  Figure 2. This shows the change of corneal endothelial cell density in postoperative periods in diabetics and non-diabetics (%). The changes were not statistically significantly different 1 week, 4 weeks, and 16 weeks after cataract surgery both in diabetics and in non-diabetics (P>0.05).

Reference

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