J Korean Ophthalmol Soc.  2004 Sep;45(9):1522-1527.

Ocular Findings Associated with Peripapillary Myelinated Nerve Fibers of 3 Clock Hours or More

• Hwang JM

Abstract

PURPOSE
We evaluated the ocular findings associated with peripapillary myelinated nerve fibers of 3 clock hours or more in 15 patients. METHODS: Ophthalmologic examination was performed in 15 patients with peripapillary myelinated nerve fibers of 3 clock hours or more. Twelve younger patients who wanted occlusion therapy were enrolled into a therapeutic trial with spectacle correction and occlusion for amblyopia. RESULTS: Thirteen out of the 15 patients presented with varying degrees of anisomyopia and amblyopia. The final visual acuities of the 12 younger patients with spectacle correction and occlusion for amblyopia were 0.5 or better in 5, between 0.1 and 0.5 in 4, and worse than 0.1 in 3. Two patients showed no ocular abnormalities except negligible refractive errors. Five out of 13 patients with amblyopia showed constant exotropia and one showed intermittent exotropia in the eyes with myelinated nerve fibers. CONCLUSIONS: Most of the patients with peripapillary myelinated nerve fibers of 3 clock hours or more showed anisomyopia and amblyopia. As some patients responded to spectacle correction and occlusion therapy for amblyopia, aggressive amblyopia therapy should be considered even in patients with myelinated nerve fibers.

Keyword

Amblyopia; Anisomyopia; Myelinated nerve fibers; Occlusion therapy

MeSH Terms

Amblyopia
Exotropia
Humans
Myelin Sheath*
Nerve Fibers, Myelinated*
Refractive Errors
Visual Acuity