J Korean Ophthalmol Soc.  2002 Aug;43(8):1522-1527.

The Effect of Ginkgo Biloba to Retinal Microcirculation

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Dong-A University, Pusan, Korea. shrho@donga.ac.kr

Abstract

PURPOSE: We evaluated the microcircular changes of optic disc, peripapillary and macular area in healthysubjects who had taken Gingko biloba extract.
METHODS
10 healthy subjects (20 eyes) took Gingko biloba extract 40mg three times daily. Confocal scanning laser flowmetry (Heidelberg Retina Flowmetry, Heidelberg Engineering, Heidelberg, Germany) was used to measure the changes of microcirculation at before and after 2, 4 hours, 1 day, 1, 2, 3, 4 weeks.
RESULTS
After administration of Gingko biloba extract, blood velocity, blood flow and blood volume in optic disc, peripapillary and macular area increased in all periods but statistically significant in 1 day, 1, 2, 3, 4 weeks except blood volume of macular area in 1 day. No side effects related to Gingko biloba extract were found.
CONCLUSIONS
Gingko biloba extract increased microcircular blood velocity, flow, and volume in healthysubjects.

Keyword

Ginkgo biloba; Blood flow; Blood volume; Blood velocity

MeSH Terms

Blood Flow Velocity
Blood Volume
Ginkgo biloba*
Microcirculation*
Retina
Retinaldehyde*
Rheology
Retinaldehyde
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