Clinical Outcome of Spontaneously Regressed ROP

Chung, Tae Young; Yu, Young Suk

Abstract

PURPOSE: To evaluate the fundus findings, refractive error, strabismus, and visual outcomes in spontaneously regressed ROP patients, and to compare the results with that of the full term infants.
METHODS
The medical records of 126 eyes in 67 spontaneously regressed ROP patients were retrospectively reviewed for refraction, IOP, ERG findings, fundus findings, and strabismus. Refraction and strabismus were compared according to active ROP stages and the presence of plus disease. Bestcorrected visual acuity (BCVA) was evaluated for 40 eyes in 22 patients who were able to check the corrected visual acuity.
RESULTS
All spontaneously regressed ROP patients had no cicatricial changes on fundus examination, and had normal IOP, and ERG findings. The incidence of myopia over 2.0 D and high myopia over 6.0 D was 18.2% and 7.1% respectively, and 10.5% had strabismus. Refraction and strabismus was not significantly different according to either active ROP stag or the presence of plus disease. For 40 eyes in 22 patients, 92.5% had BCVA 0.5 or better, and for 3 eyes with BCVA below 0.5, strabismic amblyopia and high myopia was the main cause of poor vision.
CONCLUSIONS
All spontaneously regressed ROP patients had no cicatricial changes on fundus examination, and most of the patients had favorable visual outcomes. The incidence of myopia was not different from that of the term infants. The incidence of strabismus was higher than that of the term infants, but it was not different from that of the premature infants without ROP.