J Korean Ophthalmol Soc.  1988 Feb;29(1):69-75.

Protease Activities in Various Kinds of Enzymatic Cleaners for Contact Lenses

• Kim JH
• Tanouchi H

Abstract

UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effctive for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high proteasea activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10 ~ 30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.

MeSH Terms

Contact Lenses*
Contact Lenses, Hydrophilic