J Korean Rheum Assoc.  2005 Sep;12(3):213-221.

Clinical Analysis of Relapsing Polychondritis: 16 Cases in Korea

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. ysong@snu.ac.kr
  • 2Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea.

Abstract


OBJECTIVE
To investigate the clinical characteristics of relapsing polychondritis (RP) in Korea.
METHODS
We retrospectively reviewed 16 patients with RP who were diagnosed at Seoul National University Hospital and Gyeongsang National University Hospital in the period from July 1987 to August 2003.
RESULTS
There were 9 males and 7 females, the mean age was 45.4+/-12.8 years. The frequency of clinical manifestation was as follows; auricular chondritis (81.3%), nasal chondritis (68.8%), ocular inflammation (56.3%), respiratory tract involvement (56.3%), arthritis (50%) and audio-vestibular damage (25%). Westergren erythrocyte sedimentation rate (ESR) was elevated in 53.3% and antinuclear antibody (ANA) was positive in 20% of study patients. Rheumatoid factor was negative in all cases.
CONCLUSION
Clinical manifestations were comparable to the reports of Western countries. However, the frequency of arthritis was lower in Korean patients with RP than Western reports.

Keyword

Relapsing polychondritis; Clinical characteristics

MeSH Terms

Antibodies, Antinuclear
Arthritis
Blood Sedimentation
Female
Humans
Inflammation
Korea*
Male
Polychondritis, Relapsing*
Respiratory System
Retrospective Studies
Rheumatoid Factor
Seoul
Antibodies, Antinuclear
Rheumatoid Factor
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