J Korean Soc Biol Psychiatry.  1998 Nov;5(2):248-252.

The Relation of Antipsychotic Drug Induced-Acute Dystonia and Serum Iron Level

• Lee DJ
• Park IJ
• Kwon YJ
• Jeong HY
• Han SH

Abstract

OBJECT: This study was performed in order to examine the correlation between acute neuroleptic-induced dystonic reactions and serum iron level. METHOD: Serum iron levels were measured in psychiatric inpatients who had developed acute neuroleptic-induced dystonia(N=41) and in control patients with no history of acute dystonic reactions(N=37). Serum iron levels were compared in acute dystonic inpatients before starting treatment with neuroleptics and after acute dystonic reaction.
RESULTS
The patients exhibiting acute dystonic reactions had significantly lower serum iron levels than the patients without acute dystonic reactions.
CONCLUSION
This result supports an association between low serum iron and the occurrence of neuroleptic-induced acute dystonic reactions.

MeSH Terms

Antipsychotic Agents
Dystonia*
Humans
Inpatients
Iron*
Antipsychotic Agents
Iron