J Korean Epilepsy Soc.  2010 Jun;14(1):27-30.

Fahr's Syndrome Presenting with Recurrent Epileptic Seizures

Affiliations
  • 1Department of Neurology, Kosin University College of Medicine, Busan, Korea. nekim@ns.kosinmed.or.kr

Abstract

Calcium deposits in the basal ganglia and in the other areas of the brain may occur as idiopathic disease or secondary to metabolic disturbances including hypoparathyroidism. Fahr's syndrome is characterized by secondary cerebral calcification and variable clinical manifestations of movement disorder, cognitive impairment, and behavioral changes. We report a 48 year-old man with Fahr's syndrome due to idiopathic hypoparathyroidism who presented with recurrent epileptic seizures. Brain CT showed multiple calcifications of the Fahr type in the basal ganglia, thalami, cerebellar white matter and dentate nuclei, and centrum seiovale. Brain MRI diffusion-weighted image showed high signal intensity in the right anterior temporal region.

Keyword

Fahr's syndrome; Epileptic seizure; Hypoparathyroidism

MeSH Terms

Basal Ganglia
Brain
Calcium
Epilepsy
Humans
Hypoparathyroidism
Movement Disorders
Calcium
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