J Korean Soc Emerg Med.  2012 Dec;23(6):825-830.

The Prognostic Abilities of Severity Scoring Systems for Patients with Septic Shock

• Lee HJ
• Chung TN
• Lee JY
• Bae JK
• Kim EC
• Choi SW
• Kim OJ
• Cho YK

Abstract

PURPOSE
The aim of the study was to validate abbreviated mortality in emergency department sepsis (MEDS) scoring system by comparing it with original MEDS score and to assess the prognostic value of other prognostic factor for sepsis patients including multiple organ dysfunction score (MODS), sepsis-related organ failure assessment (SOFA) score, and serum procalcitonin level.
METHODS
Adult patients visiting emergency department (ED) with evidence of septic shock were enrolled to the study. MEDS score, MODS, and SOFA score were calculated based on initial clinical data. Receiver-operating characteristics (ROC) analyses were used to assess the prognostic factors for predicting mortality. Kaplan-Meier survival analyses (KMSA) were used to determine whether the prognostic factors had correlation with survival time.
RESULTS
Only MODS showed significant predicting power for mortality (p=0.003, area under curve=0.625). Estimated median survival of all the patients calculated by KMSA was 11.0 (standard error 1.7) days, and predefined criteria of all prognostic factors showed significant differences in survival time.
CONCLUSION
MEDS, abbreviated MEDS, MODS, and SOFA scoring systems were useful factors for predicting survival time of septic shock patients visiting ED.

Keyword

Septic shock; Prognosis; Survival; MEDS

MeSH Terms

Adult
Calcitonin
Emergencies
Humans
Multiple Organ Failure
Organ Dysfunction Scores
Prognosis
Protein Precursors
Sepsis
Shock, Septic
Calcitonin
Protein Precursors