J Korean Soc Endocrinol.  1998 Sep;13(3):489-494.

Wernicke's Encephalopathy evoked by Hyperemesis Gravidarum and Hyperthyroidism

Abstract

Wernickes encephalopathy is an illness characterized by mental disturbance, paralysis of eye movements and ataxia of gait. The specific factor for most, if not all, of these symptoms is a deficiency of thiamine. Wemicke's encephalopathy mostly occurs in developing countries when the patient is in a state such as nutritionally deprived state, anorexia nervosa, stomach cancer, long duration of parenteral nutrition. Wernickes encephalopathy was recognized as a complication of hyperemesis of pregnancy in 1914. Unfortunately, cases continue to occur. We present here a case of Wernickes encephalopathy in a 36-year-old pregnant woman. We discuss the clinical picture, histopathology, radiology, therapeutic management and prognosis with review of the literature.


MeSH Terms

Adult
Anorexia Nervosa
Developing Countries
Eye Movements
Female
Gait Ataxia
Humans
Hyperemesis Gravidarum*
Hyperthyroidism*
Paralysis
Parenteral Nutrition
Pregnancy
Pregnant Women
Prognosis
Radiation Oncology
Stomach Neoplasms
Thiamine
Wernicke Encephalopathy*
Thiamine
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