J Korean Child Neurol Soc.  2010 May;18(1):108-111.

Guillain-Barre Syndrome Caused by Swine Influenza(H1N1) Vaccination: A Case Report

Affiliations
  • 1Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea. essuh@hosp.sch.ac.kr

Abstract

Guillain-Barre syndrome(GBS), characterized by Landry's ascending paralysis, has been known to be caused by some viruses and some vaccinations. We report a case of GBS caused by swine influenza vaccination. The patient presented with rapidly progressive ascending paralysis after vaccination. After intravenous immunoglobulin therapy and other conservative treatments, he recovered without any complications. Whilst the patient did not exhibit typical GBS features, we still suspect that this case represents a variant of GBS. GBS secondary to vaccination is rare and the association has yet to be proven. We therefore recommend that swine influenza vaccination continue despite this apparent case of secondary GBS.

Keyword

Influenza A virus; H1N1 subtype

MeSH Terms

Guillain-Barre Syndrome
Humans
Immunization, Passive
Influenza A virus
Influenza, Human
Paralysis
Swine
Vaccination
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