J Dent Rehabil Appl Sci.  2016 Jun;32(2):130-134. 10.14368/jdras.2016.32.2.130.

Non Hodgkin lymphoma in the maxillary sinus mimicking dental abscess: a case report

• Song JY

• KMID: 2328895
• DOI: http://doi.org/10.14368/jdras.2016.32.2.130

Abstract

Malignant lymphomas are neoplasms with diffuse proliferation of neoplastic lymphocytes and their precursor cells. Diffuse large B-cell lymphoma, which is a subtype of non-Hodgkin's lymphomas, rarely occurs in the head and neck area and is especially rare in the maxillary sinus. We report a case of a 76-year-old female patient who was referred to the oral and maxillofacial surgery office for evaluation of a dental abscess as a clinical diagnosis. Laboratory tests revealed no signs of inflammation or infection; therefore, incisional biopsy was performed. The final diagnosis was diffuse large B-cell lymphoma in the maxillary sinus. Here we describe this case with a review of relevant literature.

Keyword

maxillary sinus; non-hodgkin lymphoma; diffuse large B-cell lymphoma; dental abscess

MeSH Terms

Abscess*
Aged
Biopsy
Diagnosis
Female
Head
Humans
Inflammation
Lymphocytes
Lymphoma
Lymphoma, B-Cell
Lymphoma, Non-Hodgkin*
Maxillary Sinus*
Neck
Surgery, Oral

Figure

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  Fig. 1 Swelling and redness on the right infraorbital area was detected in the clinical photography.

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  Fig. 2 In the dental panoramic view, no specific findings were detected.

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  Fig. 3 Computed tomography (CT) revealed loss of bony continuity of lateral wall and upper wall of the right maxillary sinus.

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  Fig. 4 In the magnetic resonance imaging (MRI) revealed mild enhancing large mass in the right maxillary sinus (T2 weighted axial image).

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  Fig. 5 A positron emission tomography/computed tomography (PET/CT) revealed large hypermetabolic lesion in the right maxillary area and in the colon or small bowel.

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  Fig. 6 The histological analysis revealed diffuse proliferation of large neoplastic B cell with large nuclei (Hematoxylin eosin staining, (A) ×200, (B) ×400).

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  Fig. 7 The immunohistochemical staining (×20, (A) CD45, (B) CD 3, (C) vimentin).

Reference

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