Soonchunhyang Med Sci.  2016 Jun;22(1):27-30. 10.0000/sms.2016.22.1.27.

Recurrent Impetigo Herpetiformis of Pregnancy Successfully Treated with Acitretin

Affiliations
  • 1Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. drsook@schmc.ac.kr
  • 2Department of Pathology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.

Abstract

Impetigo herpetiformis (IH) is an extremely rare pustular dermatosis of pregnancy with typical onset during the second or third trimester of pregnancy and generally rapid resolution after delivery. Recurrent case of IH in subsequent pregnancy tend to earlier onset and greater severity. We report a 33-year-old pregnant woman, with a history of mild IH in the first pregnancy, who presented with generalized lesions at nearly 29 weeks' gestation. Her condition had become worse suddenly at 34 weeks' gestation. She developed fever, small for gestational age, and gait disturbance due to ache in both thighs. So we decided to terminate the pregnancy by repeat cesarean section. After delivery, her skin lesions had worsen rapidly in spite of treatment with corticosteroids. So she was treated with a large dose of acitretin. Three months after her delivery, her skin was returned to original state, except for residual pigmentation. In conclusion, our case indicates that clinicians should be aware of the possibility of sudden deterioration of the maternal lesions and fetal condition associated with IH.

Keyword

Impetigo herpetiformis; Pregnancy; Acitretin

MeSH Terms

Acitretin*
Adrenal Cortex Hormones
Adult
Cesarean Section, Repeat
Female
Fever
Gait
Gestational Age
Humans
Impetigo*
Pigmentation
Pregnancy Trimester, Third
Pregnancy*
Pregnant Women
Skin
Skin Diseases
Thigh
Acitretin
Adrenal Cortex Hormones
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