J Korean Surg Soc.  2013 Jul;85(1):43-46.

Primary leiomyosarcoma of the thyroid

• Ege B
• Leventoglu S

Abstract

A 56-year-old male with primary leiomyosarcoma of the thyroid is presented. The paucity of diagnostic maneuvers, including tumor markers, fine needle aspiration, and frozen section biopsy, are stressed, in addition to the fulminate course of the disease.

Keyword

Thyroid; Leiomyosarcoma

MeSH Terms

Biopsy
Biopsy, Fine-Needle
Biomarkers, Tumor
Frozen Sections
Humans
Leiomyosarcoma
Male
Thyroid Gland

Figure

• 

  Fig. 1 Ultrasound of neck showed 2.71 cm × 2.59 cm solid nodule arising from left thyroid lobe.

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  Fig. 2 Hematoxylin-eosin staining showed spindle-shaped cells with hyperchromatic, blunt-ended nuclei and abundant eosinophilic cytoplasm (H&E, ×10).

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  Fig. 3 The tumor was strongly positive for smooth muscle actin, positive for desmin, and negative for pancytokeratin, suggesting primary leiomyosarcoma of thyroid. (A) Positive for desmin (×10). (B) Negative for pancytokeratin (×10). (C) Strongly positive for smooth muscle actin (×10).

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