J Korean Soc Vasc Surg.  2001 Apr;17(1):120-125.

Chronic Arterial Occlusion by Hypercoagulable State 2 cases report (Antiphospholipid syndrome and Polycythemia vera)

• Chang JH
• Kim SH
• Jeong JH
• Kim CY
• Min YD

Abstract

Hypercoagulable states (HS) are well recognized as a cause of arterial and venous thromboembolism. These coditions are usually associated with abnormalities in natural anticoagulants, the fibrolytic system, or platelet aggregation. Primary arterial thrombosis is unusual in the young population. Hypercoagulable states are usually acquired, but they may be congenital. The congenital states occur in response to deficiency of protein C, protein S, AT-III. And the acquired states occur in response to disease, in response to tissue injury, or in response to therapy. But in this country, we have no any data of prevalence ratio of HS, which developed symptome of arterial occlusion, cases of bypass and theapeutic modality. We experienced two cases of acquired HS that is antiphospholipid syndrome and polycythemia. Based on our experience with this patients and a review of the literature on the previously reported. And we suggest that there will be made for the purpose of studying non-atherosclerotic lower extremity occlusion registry which developed in our country through the small study group.

Keyword

Hypercoagulable state; Chronic arterial occlusion

MeSH Terms

Anticoagulants
Antiphospholipid Syndrome
Humans
Lower Extremity
Platelet Aggregation
Polycythemia*
Prevalence
Protein C
Protein S
Thrombosis
Venous Thromboembolism
Anticoagulants
Protein C
Protein S