J Korean Soc Radiol.  2011 Sep;65(3):271-274.

A Case of Castleman's Disease Arising from the Greater Omentum

Affiliations
  • 1Department of Radiology, Dong-A University College of Medicine, Busan, Korea. medcarrot@naver.com

Abstract

Castleman's disease is a rare benign lymphoproliferative disorder of unknown etiology with about 70% of cases occurring in the thorax. However, the disorder can also occur in an extrathoracic site where lymphoid tissue is present. We report here a rare case of omental Castleman's disease in a 69-year-old female patient, imaged by three cross-sectional modalities: US, CT, and MRI with gadolinium.


MeSH Terms

Aged
Female
Gadolinium
Giant Lymph Node Hyperplasia
Humans
Lymphoid Tissue
Lymphoproliferative Disorders
Omentum
Thorax
Gadolinium

Figure

  • Fig. 1 A. CT scan of the patient shows a well-circumscribed, well enhancing 3.3 × 2.7 cm mass in the greater omentum (arrow). B. On ultrasonography, the mass shows heterogeneous hypoechogenicity compared to muscle with internal vascularity. C, D. On the MRI, the mass is homogenous hypointense with T1 weighting (C) and hyperintense with T2 weighting (D), compared to the signal intensity of the muscles. E, F. On histopathologic examination, diffusely scattered large follicles with markedly expanded mantle zone (E) (H&E stain, × 20) are present. The enlarged lymphoid follicle shows a small germinal, markedly vascular proliferation, and a broad mantle zone composed of a concentric layer of lymphocytes resulting in an onion skin appearance (F) (H&E stain, × 200).


Reference

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