Ultrasonography.  2016 Apr;35(2):164-167. 10.14366/usg.15063.

Signet-ring cell carcinoma of the appendix: a case report with an emphasis on sonographic findings

• Cho YJ
• Kim HJ
• Jang SK
• Yeon JW
• Kim KH
• Paik SY

• KMID: 2319331
• DOI: http://doi.org/10.14366/usg.15063

Abstract

In this report, we present a rare case of primary signet-ring cell carcinoma of the appendix in a 51-year-old woman with right lower quadrant pain. Since non-specific concentric appendiceal wall thickening was found in a radiologic evaluation, it was misdiagnosed as non-tumorous appendicitis. An in-depth examination of the correlation between sonographic and histopathologic findings demonstrated that a single markedly thickened hypoechoic layer was well correlated with the diffuse infiltration of tumor cells in both the submucosal and muscle layers. If this sonographic finding is observed in certain clinical settings, such as potential ovarian and peritoneal metastasis, submucosal infiltrative tumors, including signet-ring cell carcinoma, should be considered in the differential diagnosis.

Keyword

Carcinoma, signet ring cell; Ultrasonography; Appendix

MeSH Terms

Appendicitis
Appendix*
Carcinoma, Signet Ring Cell
Diagnosis, Differential
Female
Humans
Middle Aged
Neoplasm Metastasis
Ultrasonography*