Tuberc Respir Dis.
1998 Apr;45(2):421-428.
A Case of Pulmonary Eosinophilic Granuloma in a Passive-Smoking Reproductive Female
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea.
- 2Department of Thoracic Surgery, College of Medicine, Yonsei University, Seoul, Korea.
- 3Department of Radiology, College of Medicine, Yonsei University, Seoul, Korea.
- 4Department of Pathology, College of Medicine, Yonsei University, Seoul, Korea.
Abstract
- Pulmonary eosinophilic granuloma, a rare form of Langerhans cell histiocytosis confined to lung, has no known etiology and variable natural history. It is characterized by discrete proliferation of Langerhans cells. It is known that over 90% of the patients are cigarette smokers, and it is rarely reported in non- or passive-smoking patients, especially female. Here we describe a case of pulmonary eosinophilic granuloma in a passive-smoking, reproductive female patient presented with spontaneous pneumothorax. We identified S-100 and CDla positive histiocytes on immunohistochemical stain of the lung tissue obtained by open lung biopsy.
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