Korean J Urol.  2011 Jun;52(6):428-430.

Solitary Penile Neurofibroma with Erectile Dysfunction

• Ji YH
• Cheon SH
• Lee JH
• Moon HH
• Kim YM
• Park S
• Park S

Abstract

Neurofibromas of the penis, although very rare, are often associated with neurofibromatosis type 1. Primary solitary neurofibromas of the penis are extremely rare. We describe a 37-year-old man with a solitary neurofibroma in the dorsum of the penis. The patient reported difficulty with sexual intercourse owing to a penile mass and erectile dysfunction. After surgical excision of the neurofibroma, he had no pain and a normal sensation of the penile glans, and his erectile dysfunction improved. At the present time, 26 months after surgery, there has been no evidence of tumor recurrence.

Keyword

Erectile dysfunction; Neurofibroma; Penis

MeSH Terms

Adult
Coitus
Erectile Dysfunction
Humans
Male
Neurofibroma
Neurofibromatosis 1
Penis
Recurrence
Sensation

Figure

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  FIG. 1 T2-weighted MR image showing an ovoid mass with a high signal intensity rim and a surrounding dark signal intensity rim.

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  FIG. 2 Gross appearance of the exposed neurofibroma on the penile shaft.

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  FIG. 3 Microphotography showing spindle-shaped cells with wavy nuclei in fascicles (H&E, ×400).

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  FIG. 4 Tumor cells are uniformly reactive for S-100 protein (×100).

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