Korean J Urol.  2012 Jun;53(6):424-430.

Predictive Factors of the Outcome of Extracorporeal Shockwave Lithotripsy for Ureteral Stones

Affiliations
  • 1Department of Urology, Yeungnam University College of Medicine, Daegu, Korea. htkim-1212@hanmail.net

Abstract

PURPOSE
Extracorporeal Shock Wave Lithotripsy (ESWL) has shown successful outcomes for ureteral stones. We investigated predictive factors for failure of ESWL for treating ureteral stones.
MATERIALS AND METHODS
A total of 153 patients who underwent ESWL between July 2006 and July 2009 for ureteral stones diagnosed by non-enhanced spiral computed tomography were divided into two groups: (group A, stone size < or =10 mm; and group B, stone size >10 mm). The failure was defined as remnant stones >4 mm. We assessed age, sex, body mass index, stone size, laterality, location, skin-to-stone distance (SSD), Hounsfield unit, and the presence of secondary signs (hydronephrosis, renal enlargement, perinephric fat stranding, and tissue rim sign). We analyzed predictive factors by using logistic regression in each group.
RESULTS
The success rates were 90.2% and 68.6% in group A and B, respectively. In the univariate analysis of each group, stone size, SSD, and all secondary signs showed statistically significant differences in terms of the outcome of ESWL (p<0.05). In the multivariate logistic regression, stone size (odds ratio [OR], 50.005; 95% confidence interval [CI], 6.207 to 402.852) was an independent predictive factor in group A. The presence of perinephric fat standing (OR, 77.634; 95% CI, 1.349 to 446.558) and stone size (OR, 19.718; 95% CI, 1.600 to 243.005) were independent predictive factors in group B.
CONCLUSIONS
Stone size is an independent predictive factor influencing failure of ESWL for treating ureteral stones. In larger ureteral stones (>10 mm), the presence of perinephric fat stranding is also an independent predictive factor.

Keyword

Lithotripsy; Treatment outcome; Ureteral calculi

MeSH Terms

Body Mass Index
Humans
Lithotripsy
Logistic Models
Shock
Silver Sulfadiazine
Tomography, Spiral Computed
Treatment Outcome
Ureter
Ureteral Calculi
Silver Sulfadiazine

Figure

  • FIG. 1 The non-enhanced computed tomography scan images of secondary signs. (A) Hydronephrosis of the right kidney. (B) Renal enlargement and perinephric fat stranding of the left kidney (arrowhead). (C) Tissue rim sign of the left ureter (arrow).


Reference

1. Chaussy C, Schmiedt E, Jocham D, Brendel W, Forssmann B, Walther V. First clinical experience with extracorporeally induced destruction of kidney stones by shock waves. J Urol. 1982. 127:417–420.
2. Segura JW, Preminger GM, Assimos DG, Dretler SP, Kahn RI, Lingeman JE, et al. The American Urological Association. Ureteral Stones Clinical Guidelines Panel summary report on the management of ureteral calculi. J Urol. 1997. 158:1915–1921.
3. Robert M, Delbos O, Guiter J, Grasset D. In situ piezoelectric extracorporeal shock wave lithotripsy of ureteric stones. Br J Urol. 1995. 76:435–439.
4. Lingeman JE, Matlaga BR. Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Surgical management of upper urinary tract calculi. Campbell-Walsh urology. 2010. 10th ed. Philadelphia: Saunders;1375–1377.
5. Erturk E, Herrman E, Cockett AT. Extracorporeal shock wave lithotripsy for distal ureteral stones. J Urol. 1993. 149:1425–1426.
6. Pareek G, Armenakas NA, Fracchia JA. Hounsfield units on computerized tomography predict stone-free rates after extracorporeal shock wave lithotripsy. J Urol. 2003. 169:1679–1681.
7. Joseph P, Mandal AK, Singh SK, Mandal P, Sankhwar SN, Sharma SK. Computerized tomography attenuation value of renal calculus: can it predict successful fragmentation of the calculus by extracorporeal shock wave lithotripsy? A preliminary study. J Urol. 2002. 167:1968–1971.
8. Pareek G, Armenakas NA, Panagopoulos G, Bruno JJ, Fracchia JA. Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. Urology. 2005. 65:33–36.
9. Seitz C, Fajkovic H, Waldert M, Tanovic E, Remzi M, Kramer G, et al. Extracorporeal shock wave lithotripsy in the treatment of proximal ureteral stones: Does the presence and degree of hydronephrosis affect success? Eur Urol. 2006. 49:378–383.
10. Kim HS, Jang SW, Jeong YB, Kim YG, Kim JS. The usefulness of unenhanced helical computerized tomography in patients with urinary calculi. Korean J Urol. 2003. 44:796–800.
11. Song DW, Jeong TY, Lee SI, Kim DJ. Predicting factors for spontaneous passage of ureteral calculi based on unenhanced helical CT findings. Korean J Urol. 2008. 49:1094–1099.
12. Kang YI, Moon HY, Kim CS. Relationship between the success of extracorporeal shock wave lithotripsy (ESWL) and the degree of hydronephrosis when treating patients with upper ureteral stones. Korean J Urol. 2007. 48:422–427.
13. Türkbey B, Akpinar E, Ozer C, Turkbey EB, Eken V, Karçaaltincaba M, et al. Multidetector CT technique and imaging findings of urinary stone disease: an expanded review. Diagn Interv Radiol. 2010. 16:134–144.
14. Shiroyanagi Y, Yagisawa T, Nanri M, Kobayashi C, Toma H. Factors associated with failure of extracorporeal shock-wave lithotripsy for ureteral stones using Dornier lithotripter U/50. Int J Urol. 2002. 9:304–307.
15. Abdel-Khalek M, Sheir K, Elsobky E, Showkey S, Kenawy M. Prognostic factors for extracorporeal shock-wave lithotripsy of ureteric stones--a multivariate analysis study. Scand J Urol Nephrol. 2003. 37:413–418.
16. Argyropoulos AN, Tolley DA. Failure after shockwave lithotripsy: is outcome machine dependent? Int J Clin Pract. 2009. 63:1489–1493.
17. Hatiboglu G, Popeneciu V, Kurosch M, Huber J, Pahernik S, Pfitzenmaier J, et al. Prognostic variables for shockwave lithotripsy (SWL) treatment success: no impact of body mass index (BMI) using a third generation lithotripter. BJU Int. 2011. 108:1192–1197.
18. Kim HH, Lee JH, Park MS, Lee SE, Kim SW. In situ extracorporeal shockwave lithotripsy for ureteral calculi: investigation of factors influencing stone fragmentation and appropriate number of sessions for changing treatment modality. J Endourol. 1996. 10:501–505.
19. Rush E, Plank L, Chandu V, Laulu M, Simmons D, Swinburn B, et al. Body size, body composition, and fat distribution: a comparison of young New Zealand men of European, Pacific Island, and Asian Indian ethnicities. N Z Med J. 2004. 117:U1203.
20. Ng CF, Siu DY, Wong A, Goggins W, Chan ES, Wong KT. Development of a scoring system from noncontrast computerized tomography measurements to improve the selection of upper ureteral stone for extracorporeal shock wave lithotripsy. J Urol. 2009. 181:1151–1157.
21. Wiesenthal JD, Ghiculete D, D'A Honey RJ, Pace KT. Evaluating the importance of mean stone density and skin-to-stone distance in predicting successful shock wave lithotripsy of renal and ureteric calculi. Urol Res. 2010. 38:307–313.
22. Perks AE, Schuler TD, Lee J, Ghiculete D, Chung DG, D'A Honey RJ, et al. Stone attenuation and skin-to-stone distance on computed tomography predicts for stone fragmentation by shock wave lithotripsy. Urology. 2008. 72:765–769.
23. Saw KC, McAteer JA, Fineberg NS, Monga AG, Chua GT, Lingeman JE, et al. Calcium stone fragility is predicted by helical CT attenuation values. J Endourol. 2000. 14:471–474.
24. Gupta NP, Ansari MS, Kesarvani P, Kapoor A, Mukhopadhyay S. Role of computed tomography with no contrast medium enhancement in predicting the outcome of extracorporeal shock wave lithotripsy for urinary calculi. BJU Int. 2005. 95:1285–1288.
25. Ege G, Akman H, Kuzucu K, Yildiz S. Acute ureterolithiasis: incidence of secondary signs on unenhanced helical CT and influence on patient management. Clin Radiol. 2003. 58:990–994.
26. Boulay I, Holtz P, Foley WD, White B, Begun FP. Ureteral calculi: diagnostic efficacy of helical CT and implications for treatment of patients. AJR Am J Roentgenol. 1999. 172:1485–1490.
27. Seitz C, Memarsadeghi M, Fajkovic H, Tanovic E. Secondary signs of non-enhanced CT prior to laser ureterolithotripsy: is treatment outcome predictable? J Endourol. 2008. 22:415–418.
28. Takahashi N, Kawashima A, Ernst RD, Boridy IC, Goldman SM, Benson GS, et al. Ureterolithiasis: can clinical outcome be predicted with unenhanced helical CT? Radiology. 1998. 208:97–102.
29. Kunin M. Bridging septa of the perinephric space: anatomic, pathologic, and diagnostic considerations. Radiology. 1986. 158:361–365.
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