Korean J Urol.  2010 Feb;51(2):115-121.

Comparative Analysis of the Efficacy and Safety of Photoselective Vaporization of the Prostate for Treatment of Benign Prostatic Hyperplasia according to Prostate Size

• Park JH
• Son H
• Paick JS

Abstract

PURPOSE: This study was conducted to perform a comparative analysis of the efficacy and safety of photoselective vaporization of the prostate (PVP) for treatment of benign prostatic hyperplasia (BPH) in men with a prostate volume greater than 60 cc.
MATERIALS AND METHODS
The clinical data of 249 men with symptomatic BPH who underwent PVP between January 2006 and June 2008 were retrospectively analyzed. All patients were classified into two groups according to their prostate volume (group A, <60 cc; group B, > or =60 cc). The preoperative evaluation included a digital rectal exam, urinalysis, prostate-specific antigen levels, International Prostate Symptom Score (IPSS), quality of life (QoL) score, maximal flow rate (Qmax), postvoid residual urine volume (PVR), and transrectal ultrasonography. The total operative time, used energy (kJ), urethral Foley catheter indwelling period, and the number of hospital days were recorded afterward. The IPSS, QoL score, Qmax, and PVR were evaluated at 1, 3, 6, and 12 months postoperatively.
RESULTS
In both groups, significant improvements in the subjective and objective voiding parameters were achieved and these improvements were sustainable for at least 1 year with minimal complications. During the follow-up period, the PVR in group B significantly increased. Retrograde ejaculation and urethral stricture were the common complications in both groups. There was no significant difference in the incidence rate.
CONCLUSIONS
PVP is safe and efficacious, with durable results for men with symptomatic BPH and large prostate volumes.

Keyword

Prostatic hyperplasia; Laser therapy; Comparative study

MeSH Terms

Catheters
Ejaculation
Follow-Up Studies
Humans
Incidence
Laser Therapy
Male
Operative Time
Prostate
Prostate-Specific Antigen
Prostatic Hyperplasia
Quality of Life
Retrospective Studies
Urethral Stricture
Urinalysis
Volatilization
Prostate-Specific Antigen

Figure

• 

  FIG. 1 Postoperative follow-up outcome parameters of patients who underwent PVP according to prostate size. IPSS: International Prostate Symptom Score, QoL: quality of life, Qmax: maximal urinary flow rate, PVR: postvoid residual volume, Group A: less than 60 ml, Group B: 60 ml or more, a: p<0.01, b: p<0.05, c: p=0.119.

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