Pediatr Allergy Respir Dis.  2003 Sep;13(3):180-188.

The Allergen Sensitization, Family History, Diet Pattern in Atopic Dermatitis under 2 Years of Age

Affiliations
  • 1Department of Pediatrics, College of Medicine, Pocheon University, Sungnam, Korea. kkoma75@hanmail.net

Abstract

PURPOSE
This study is intended to investigate results of skin prick tests, family history, and diet pattern in patients under 2 years of age diagnosed with atopic dermatitis (AD). METHODS: A total of 82 AD patients and 53 controls participated in this study. They visited outpatient department of Pediatrics in Pundang Cha hospital from July 2002 to May 2003. Questionnaire survey about family allergy history, duration of breast feeding, time of first weaning, kinds of foods eaten from birth was performed. Skin prick tests were performed with food allergens that consisted of egg, milk, mixed bean, beef, pork, cod, mixed flour and D. f. as aeroallergen, histamine as positive control, normal saline as negative control. RESULTS: Egg (19.5%), milk (11.0%), D. f. (9.8%), cod (8.5%) were the common allergens in AD patients. Erythema and wheal size was 14.6 mm, 2.7 mm in AD patients and 8.5 mm, 1.6 mm in controls (P< 0.05). There was no significant effect of age on the skin reactivity to histamine. Odd ratio of atopy was 31.6 (95% CI: 4.2-240.3) and that of family history was 2.6 (95% CI: 1.3-5.2). The mean age of the start of weaning was 5.6 months in AD patients and 4.5 months in controls (P< 0.05). There were no significant differences in duration of breast feeding and the number of foods eaten from birth between AD patients and controls. CONCLUSION: Egg, milk, D. f., and cod were the common allergens in AD patients under 2 years of age. This means that it is necessary for AD patients to have proper guide for weaning diet and regulation of environment. Allergy history of parents has high relative risk and therefore the high risk infants require positive prophylactic counterplans for AD.

Keyword

Atopic dermatitis; Skin prick test; Food allergy

MeSH Terms

Allergens
Breast Feeding
Dermatitis, Atopic*
Diet*
Erythema
Flour
Food Hypersensitivity
Histamine
Humans
Hypersensitivity
Infant
Milk
Outpatients
Ovum
Parents
Parturition
Pediatrics
Surveys and Questionnaires
Skin
Weaning
Allergens
Histamine
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