Obstet Gynecol Sci.  2013 Sep;56(5):345-348.

Primary extraskeletal mesenchymal chondrosarcoma of the vulva

• Jeh EA
• Lee YJ
• Kim HY
• Kim A
• Lee JH

Abstract

Extraskeletal chondrosarcoma is rare, making up only 1% of reported chondrosarcoma. We experienced 3 cases of extraskeletal chondrosarcoma, especially in vulva. They were suspected as lipoma of the vulva. The patients had noticed a small but growing mass on their vulva which had been palpated earlier. The masses were excised with a 2 cm resection margin. The final pathological reports confirmed extraskeletal mesenchymal chondrosarcoma (EMC) of the vulva revealing no microscopic lesions on the resection margins. After 24 months of following from the initial diagnosis, the patients remain without evidence of any recurrent. Management of EMC is not well studied due to the rare and variable nature of the disease. However, the surgery, such as we had, is the mainstay of local treatment with studies showing better survival in patients who undergo wide surgical resection. The establishment of adjuvant systemic pharmacotherapy could be expected in the future.

Keyword

Chondrosarcoma; Extraskeletal; Vulva

MeSH Terms

Chondrosarcoma
Chondrosarcoma, Mesenchymal
Humans
Lipoma
Vulva

Figure

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  Fig. 1 (A) Hematoxylin and eosin stained photomicrograph of undifferentiated tumor cells with areas of chondroid differentiation (×25). (B) Hematoxylin and eosin stained photomicrograph showing islands of mature hyaline cartilage (red arrows) mixed with undifferentiated, small, round, mesenchymal cells (blue arrow) (× 40).

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