Nutr Res Pract.  2011 Feb;5(1):34-39.

Assessment of vitamin B6 status in Korean patients with newly diagnosed type 2 diabetes

• Ahn HJ
• Min KW
• Cho YO

Abstract

The purpose of this study was to assess vitamin B6 intake and status in Korean patients with newly diagnosed type 2 diabetes. Sixty-four patients with newly diagnosed type 2 diabetes and 8-11% glycated hemoglobin (A1C), along with 28 age-matched non-diabetic subjects, participated. Dietary vitamin B6 intake was estimated by the 24 hour recall method and plasma pyridoxal 5'-phosphate (PLP) was measured. There was a significant difference in daily total calorie intake between the diabetic and non-diabetic groups (1,917 +/- 376 vs 2,093 +/- 311 kcal). There were no differences in intake of total vitamin B6 (2.51 +/- 0.91 vs 2.53 +/- 0.81 mg/d) or vitamin B6/1,000 kcal (1.31 +/- 0.42 vs 1.20 +/- 0.32 mg) between the diabetic and non-diabetic groups, andI intakes of total vitamin B6 were above the Korean RDA in both groups (180.0 +/- 57.9 vs 179.0 +/- 65.4). There was a higher percentage of diabetic subjects whose plasma PLP concentration was < 30 nmol/L compared to non-diabetic group. Plasma PLP levels tended to be lower in the diabetic subjects than in the non-diabetic subjects, although the difference was not statistically significant due to a large standard deviation (80.0 +/- 61.2 nmol/L vs 68.2 +/- 38.5 nmol/L). Nevertheless, plasma PLP levels should be monitored in pre-diabetic patients with diabetic risk factors as well as in newly diagnosed diabetic patients for long-term management of diabetes, even though this factor is not a major risk factor that contributes to the development of degenerative complications in certain patients.

Keyword

Vitamin B6 intake; vitamin B6 status; plasma pyridoxal 5'-phosphate; type 2 diabetes

MeSH Terms

Fibrinogen
Hemoglobins
Humans
Nutrition Policy
Plasma
Pyridoxal
Risk Factors
Vitamin B 6
Vitamins
Fibrinogen
Hemoglobins
Pyridoxal
Vitamin B 6
Vitamins

Figure

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  Fig. 1 Distribution of vitamin B6 intake in non-diabetic and diabetic1) subjects. 1) Diabetic subjects had newly diagnosed type 2 diabetes with 8-11% A1C and non diabetic subjects were age-matched.

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  Fig. 2 Scatter plots of plasma PLP levels and vitamin B6 intake in non-diabetic and diabetic1) subjects. 1) Diabetic subjects had newly diagnosed type 2 diabetes with 8-11% A1C and non diabetic subjects were age-matched.

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