Long-Term Results of Transurethral Resection of the Prostate for Large Benign Prostatic Hyperplasia: A Comparative Study with Open Prostatectomy

Kwak, Dong Yun; Chang, Hyuk Soo; Park, Choal Hee; Kim, Chun Il

Abstract

PURPOSE: We compare the effectiveness and safety of transurethral resection of the prostate(TURP) with those of open prostatectomy for large benign prostatic hyperplasia(BPH), that was over 70cc of prostate volume.
MATERIALS AND METHODS
Seventy-one patients with a prostate volume of more than 70cc and who received TURP were classified to group A, while 41 patients who received open prostatectomy were classified to group B. The International Prostate Symptom Score(IPSS), maximal flow rate(Qmax) and post-voiding residual urine(PVR) volume were evaluated preoperatively and at 1, 3, 5 and over 5 years postoperatively.
RESULTS
The postoperative IPSS, Qmax and PVR were significantly improved after 1 year(p<0.05). The IPSS and Qmax showed no significant differences between the two groups for 1, 3, 5 and over 5 years after operation(p>0.05). The PVR was significantly lower in group B at 1 year post-operation(p<0.05), but there were no significant difference between the groups for 3, 5 and over 5 years after operation(p>0.05). There were 7 cases(9.8%) of re-operation and 3 cases(4.2%) of re-medication after 5 years of operation. There were no major complications for each group.
CONCLUSIONS
On comparison between TURP and open prostatectomy for the patients with large BPH, there were no significant difference in effectiveness and safety for 5 years. Even for the patients with BPH that showed a high volume, TURP is an effective operation that can replace open prostatectomy.