Korean J Urol.  2008 Apr;49(4):383-385.

Gastrointestinal Stromal Tumor of Prostate

• Park SW
• Lee W
• Huh GY
• Chung MK

Abstract

Gastrointestinal stromal tumor(GIST) are the most common mesenchymal malignancy of the gastrointestinal tract. They are diagnosed by combination of c-kit and CD34. We report a case of extragastrointestinal stromal tumor originating from the prostate diagnosed after retropubic open prostatectomy. The patient underwent additional retropubic radical prostatectomy again after 2 weeks. The possibility of secondary involvement by a rectal GIST was excluded by radiological, intraoperative and pathologic findings.

Keyword

Gastrointestinal stromal tumors; Prostate; Prostatectomy

MeSH Terms

Gastrointestinal Stromal Tumors
Gastrointestinal Tract
Humans
Prostate
Prostatectomy

Figure

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  Fig. 1. Preoperative transrectal and transabdominal ultrasonography. The large 65x75x70 mm sized prostate was well encapsulated.

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  Fig. 2. (A) Prostate is replaced by cellular tumor mass. The tumor cells are spindle shaped with little atypia. They shows mainly fascicular arrangement. (B) Compressed prostatic glands are seen on upper left field. (C) Tumor cells are strongly positive for C-kit. (D) Tumor cells are strongly positive for CD34.

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  Fig. 3. MR prostate image showing open prostatectomy state and definite fat strand between the rectum and the remaining prostate capsule.

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