Kosin Med J.  2012 Dec;27(2):105-110. 10.7180/kmj.2012.27.2.105.

The Safety of Elective Colorectal Surgery without Mechanical Bower Preparation

Affiliations
  • 1Department of Surgery, College of Medicine, Kosin University, Busan, Korea. gscrslsh@hanmail.net

Abstract


OBJECTIVES
To reduce the risk of postoperative infectious complications and anastomotic leakage in colorectal surgery, preoperative mechanical bowel preparation (MBP) is performed routinely. The aim of this study was to evaluate the safety of primary anastomosis in elective colorectal surgery without MBP.
METHODS
From Jan. 2005 to Dec. 2006, three hundred and seventy-nine patients of elective colorectal surgery with primary anastomosis were performed with MBP in 352 cases (Prep group) and without MBP in 24 cases (Non-prep group). For preoperative MBP, 4 liters of polyethylene glycol solution was administered. Postoperative infectious complications and other morbidity were reviewed with medical records and prospectively collected data.
RESULTS
Demographic, clinical and treatment characteristics did not differ significantly between the two groups. The overall rate of abdominal infectious complications (wound infection, anastomotic leak) was 2.9 % in the Prep group and 9 % in the Non-prep group (P > 0.05). Anastomotic leak occurred in nine patients (2.6%) in the Prep group and one (4.5%) in the Non-prep group.
CONCLUSIONS
The incidence of infectious complications after elective colorectal surgery without MBP did not differ significantly compare to that with MBP. However, prospective, randomized clinical trial is needed to assess the safety of primary anastomosis in elective colorectal surgery without MBP.

Keyword

Colorectal Surgery; Complication; Mechanical Bowel Preparation

MeSH Terms

Anastomotic Leak
Colorectal Surgery
Humans
Incidence
Medical Records
Polyethylene Glycols
Prospective Studies
Polyethylene Glycols

Reference

1. Nichols RL, Condon RE. Preoperative preparation of the colon. Surg Gynecol Obstet. 1971. 132:323–337.
2. Chung RS, Gurll NJ, Berglund EM. A controlled trial of whole gut lavage as a method of bowel preparation for colonic operations. Am J Surg. 1979. 137:75–81.
Article
3. Oliveira L, Wexner SD, Daniel N, DeMarta D, Weiss EG, Nogueras JJ, et al. Mechanical bowel preparation for elective colorectal surgery. A prospective, randomized, surgeon-blinded trial comparing sodium phosphate and polyethylene glycolbased oral lavage solutions. Dis Colon Rectum. 1997. 40:585–591.
Article
4. Slim K, Vicaut E, Panis Y, Chipponi J. Meta-analysis of randomized clinical trials of colorectal surgery with or without mechanical bowel preparation. Br J Surg. 2004. 91:1125–1130.
Article
5. Bucher P, Gervaz P, Soravia C, Mermillod B, Erne M, Morel P. Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery. Br J Surg. 2005. 92:409–414.
Article
6. Fa-Si-Oen P, Roumen R, Buitenweg J, van de Velde C, van Geldere D, Putter H. Mechanical bowel preparation or not? Outcome of a multicenter, randomized trial in elective open colon surgery. Dis Colon Rectum. 2005. 48:1509–1516.
Article
7. Santos JCM Jr, Batista J, Sirimarco MT, Guimaraes AS, Levy CE. Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery. Br J Surg. 1994. 81:1673–1676.
Article
8. Zmora O, Mahajna A, Bar-Zakai B, Rosin D, Hersko D, Shabtai M. Colon and rectal surgery without mechanical bowel preparation. A randomized prospective trial. Ann Surg. 2003. 237:363–367.
9. Glenn F, McSherry CK. Carcinoma of the distal large bowel: 32-year review of 1,026 cases. Ann Surg. 1966. 163:838–849.
10. Brachman PS, Dan BB, Haley RW, Hooton TM, Garner JS, Allen JR. Nosocomial surgical infections: incidence and cost. Surg Clin North Am. 1980. 60:15–25.
Article
11. Cohen SM, Wexner SD, Binderow SR, Nogueras JJ, Daniel N, Ehrenpreis ED, et al. Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods. Dis Colon Rectum. 1994. 37:689–696.
Article
12. Yoshioka K, Connolly AB, Ogunbiyi OA, Hasegawa H, Morton DG, Keighley MR. Randomized trial of oral sodium phosphate compared with oral sodium picosulphate (Picolax) for elective colorectal surgery and colonoscopy. Dig Surg. 2000. 17:66–70.
Article
13. Curran TJ, Borzotta AP. Complications of primary repair of colon injury: literature review of 2,964 cases. Am J Surg. 1999. 177:42–47.
Article
14. Conrad JK, Ferry KM, Foreman ML, Gogel BM, Fisher TL, Livingston SA. Changing management trends in penetrating colon trauma. Dis Colon Rectum. 2000. 43:466–471.
Article
15. Jung B, Påhlman L, Nyström PO, Nilsson E. Mechanical Bowel Preparation Study Group. Multicentre randomized clinical trial of mechanical bowel preparation in elective colonic resection. Br J Surg. 2007. 94:689–695.
Article
16. Contant CM, Hop WC, van't Sant HP, Oostvogel HJ, Smeets HJ, Stassen LP, et al. Mechanical bowel preparation for elective colorectal surgery: a multicentre randomized trial. Lancet. 2007. 370:2112–2117.
Article
17. Scabini S, Rimini E, Romairone E, Scordamaglia R, Damiani G, Pertile D, et al. Colon and rectal surgery for cancer without mechanical bowel preparation: one-center randomized prospective trial. World J Surg Oncol. 2010. 8:35.
Article
18. Pineda CE, Shelton AA, Hernandez-Boussard T, Morton JM, Welton ML. Mechanical bowel preparation in intestinal surgery: a meta-analysis and review of the literature. J Gastrointest Surg. 2008. 12:2037–2044.
Article
19. Pena-Soria MJ, Mayol JM, Anula-Fernandez R, Arbeo-Escolar A, Fernandez-Represa JA. Mechanical bowel preparation for elective colorectal surgery with primary intraperitoneal anastomosis by a single surgeon: interim analysis of a prospective single-blinded randomized trial. J Gastrointest Surg. 2007. 11:562–567.
Article
20. Bucher P, Gervaz P, Egger JF, Soravia C, Morel P. Morphologic alterations associated with mechanical bowel preparation before elective colorectal surgery: a randomized trial. Dis Colon Rectum. 2006. 49:109–112.
Article
21. Valantas MR, Beck DE, Di Palma JA. Mechanical bowel preparation in the older surgical patient. Curr Surg. 2004. 61:320–324.
Article
22. Güenaga KF, Matos D, Wille-Jørgensen P. Mechanical bowel preparation for elective colorectal surgery. Cochrane Database Syst Rev. 2011. (9):CD001544.
Article
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