Korean J Med Mycol.  2002 Dec;7(4):224-226.

Hyperpigmentation Due to the Overuse of Amorolfine Nail Lacquer

Affiliations
  • 1Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea. drro@orgio.net

Abstract

Amorolfine is a broad-spectrum antimycotic agent, inhibiting biosynthesis of ergosterol. It penetrates rapidly into the nail after topical application by transungual drug delivery system. Although it is considered to be relatively stable chemical substances, it may cause nail discoloration by excessive topical application and prolonged sun exposure. We report a case of toenail hyperpigmentation due to the overuse of amorolfine nail lacquer, which is the first report in Korea.

Keyword

Amorolfine; Hyperpigmentation

MeSH Terms

Drug Delivery Systems
Ergosterol
Hyperpigmentation*
Korea
Lacquer*
Nails
Solar System
Ergosterol
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